TY - JOUR
T1 - Central pain from cerebral abscess
T2 - Thalamic syndrome in aids patients with toxoplasmosis
AU - Gonzales, Gilbert R.
AU - Herskovitz, S.
AU - Rosenblum, M.
AU - Foley, K. M.
AU - Kanner, R.
AU - Brown, A.
AU - Portenoy, R. K.
PY - 1992/5
Y1 - 1992/5
N2 - We describe two patients with acquired immunodeficiency syndrome (AIDS) who developed classic thalamic syndrome (TS) due to Toxoplasma abscesses in the thalamic region. Treatment with amitriptyline provided substantial relief in both patients. Postmortem examination in one case revealed a lesion in the internal capsule and thalamic reticular nucleus. These observations indicate that (1) TS can result from an isolated lesion in the internal capsule and reticular nucleus of the thalamus, (2) cerebral abscess can cause classic TS, (3) central pain can be added to the many pain syndromes that afflict AIDS patients, and (4) an analgesic response to amitriptyline is possible in these patients.
AB - We describe two patients with acquired immunodeficiency syndrome (AIDS) who developed classic thalamic syndrome (TS) due to Toxoplasma abscesses in the thalamic region. Treatment with amitriptyline provided substantial relief in both patients. Postmortem examination in one case revealed a lesion in the internal capsule and thalamic reticular nucleus. These observations indicate that (1) TS can result from an isolated lesion in the internal capsule and reticular nucleus of the thalamus, (2) cerebral abscess can cause classic TS, (3) central pain can be added to the many pain syndromes that afflict AIDS patients, and (4) an analgesic response to amitriptyline is possible in these patients.
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U2 - 10.1212/wnl.42.5.1107
DO - 10.1212/wnl.42.5.1107
M3 - Article
C2 - 1579236
AN - SCOPUS:0026729253
SN - 0028-3878
VL - 42
SP - 1107
EP - 1109
JO - Neurology
JF - Neurology
IS - 5
ER -
