Carcinosarcoma of bladder following long-term cyclophosphamide therapy

S. H. Sigal; J. E. Tomaszewski; J. J. Brooks; A. Wein; V. A. LiVolsi

Carcinosarcoma of bladder following long-term cyclophosphamide therapy

S. H. Sigal, J. E. Tomaszewski, J. J. Brooks, A. Wein, V. A. LiVolsi

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Abstract

Since the advent of long-term cyclophosphamide therapy, an association between this agent and the subsequent development of bladder neoplasms has been documented. Only six sarcomas have been reported, to our knowledge. This report describes the first case in which a leiomyosarcoma and an invasive transitional cell carcinoma (ie, carcinosarcoma) developed in a patient with non-Hodgkin's lymphoma treated with 240 g of cyclophosphamide over a 6.5-year period.

Original language	English (US)
Pages (from-to)	1049-1051
Number of pages	3
Journal	Archives of Pathology and Laboratory Medicine
Volume	115
Issue number	10
State	Published - Jan 1 1991
Externally published	Yes

ASJC Scopus subject areas

Pathology and Forensic Medicine
Medical Laboratory Technology

Cite this

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title = "Carcinosarcoma of bladder following long-term cyclophosphamide therapy",

abstract = "Since the advent of long-term cyclophosphamide therapy, an association between this agent and the subsequent development of bladder neoplasms has been documented. Only six sarcomas have been reported, to our knowledge. This report describes the first case in which a leiomyosarcoma and an invasive transitional cell carcinoma (ie, carcinosarcoma) developed in a patient with non-Hodgkin's lymphoma treated with 240 g of cyclophosphamide over a 6.5-year period.",

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year = "1991",

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AU - Sigal, S. H.

AU - Tomaszewski, J. E.

AU - Brooks, J. J.

AU - Wein, A.

AU - LiVolsi, V. A.

PY - 1991/1/1

Y1 - 1991/1/1

N2 - Since the advent of long-term cyclophosphamide therapy, an association between this agent and the subsequent development of bladder neoplasms has been documented. Only six sarcomas have been reported, to our knowledge. This report describes the first case in which a leiomyosarcoma and an invasive transitional cell carcinoma (ie, carcinosarcoma) developed in a patient with non-Hodgkin's lymphoma treated with 240 g of cyclophosphamide over a 6.5-year period.

AB - Since the advent of long-term cyclophosphamide therapy, an association between this agent and the subsequent development of bladder neoplasms has been documented. Only six sarcomas have been reported, to our knowledge. This report describes the first case in which a leiomyosarcoma and an invasive transitional cell carcinoma (ie, carcinosarcoma) developed in a patient with non-Hodgkin's lymphoma treated with 240 g of cyclophosphamide over a 6.5-year period.

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Carcinosarcoma of bladder following long-term cyclophosphamide therapy

Abstract

ASJC Scopus subject areas

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