Carbamazepine-induced constipation

Alan B. Ettinger, Shlomo Shinnar, Mark J. Sinnett, Solomon L. Moshé

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


We report three patients who developed constipation as an adverse effect of carbamazepine (CBZ) therapy. Constipation occurred within a few days of CBZ introduction, resolved after CBZ discontinuation, and was not dose-responsive. It was refractory to the concomitant use of oral laxatives in two cases, necessitating CBZ discontinuation. In a third patient, constipation was controlled by a fiber agent, allowing continuation of CBZ therapy. Potential mechanisms for this idiosyncratic, poorly reported adverse event are discussed.

Original languageEnglish (US)
Pages (from-to)191-193
Number of pages3
JournalJournal of Epilepsy
Issue number3
StatePublished - 1992


  • Carbamazepine
  • Constipation
  • Gastrointestinal disorder

ASJC Scopus subject areas

  • General Neuroscience
  • Clinical Neurology


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