Autotransplantation of cryopreserved parathyroid tissue in man

M. F. Brennan; E. M. Brown; A. M. Spiegel; S. J. Marx; J. L. Doppman; D. C. Jones; G. D. Aurbach

doi:10.1097/00000658-197902000-00002

Autotransplantation of cryopreserved parathyroid tissue in man

M. F. Brennan, E. M. Brown, A. M. Spiegel, S. J. Marx, J. L. Doppman, D. C. Jones, G. D. Aurbach

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Human cryopreserved parathyroid autografts have been performed in six patients following reoperative parathyroid surgery. All patients were rendered hypoparathyroid by their most recent reoperation. Parathyroid tissue was successfully autotransplanted after as long as eighteen months of cryopreservation. Viability and expected in vivo function of cryopreserved parathyroid tissue may be predicted by in vitro testing of parathyroid hormone secretion in response to varying ambient calcium concentration. Parathyroid cryopreservation with subsequent autotransplantation is a practical solution to the problem of permanent hypoparathyroidism that may follow multiple surgical procedures for persistent hyperparathyroidism.

Original language	English (US)
Pages (from-to)	139-142
Number of pages	4
Journal	Unknown Journal
Volume	189
Issue number	2
DOIs	https://doi.org/10.1097/00000658-197902000-00002
State	Published - 1979
Externally published	Yes

ASJC Scopus subject areas

Surgery

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title = "Autotransplantation of cryopreserved parathyroid tissue in man",

abstract = "Human cryopreserved parathyroid autografts have been performed in six patients following reoperative parathyroid surgery. All patients were rendered hypoparathyroid by their most recent reoperation. Parathyroid tissue was successfully autotransplanted after as long as eighteen months of cryopreservation. Viability and expected in vivo function of cryopreserved parathyroid tissue may be predicted by in vitro testing of parathyroid hormone secretion in response to varying ambient calcium concentration. Parathyroid cryopreservation with subsequent autotransplantation is a practical solution to the problem of permanent hypoparathyroidism that may follow multiple surgical procedures for persistent hyperparathyroidism.",

author = "Brennan, {M. F.} and Brown, {E. M.} and Spiegel, {A. M.} and Marx, {S. J.} and Doppman, {J. L.} and Jones, {D. C.} and Aurbach, {G. D.}",

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doi = "10.1097/00000658-197902000-00002",

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AU - Brennan, M. F.

AU - Brown, E. M.

AU - Spiegel, A. M.

AU - Marx, S. J.

AU - Doppman, J. L.

AU - Jones, D. C.

AU - Aurbach, G. D.

PY - 1979

Y1 - 1979

N2 - Human cryopreserved parathyroid autografts have been performed in six patients following reoperative parathyroid surgery. All patients were rendered hypoparathyroid by their most recent reoperation. Parathyroid tissue was successfully autotransplanted after as long as eighteen months of cryopreservation. Viability and expected in vivo function of cryopreserved parathyroid tissue may be predicted by in vitro testing of parathyroid hormone secretion in response to varying ambient calcium concentration. Parathyroid cryopreservation with subsequent autotransplantation is a practical solution to the problem of permanent hypoparathyroidism that may follow multiple surgical procedures for persistent hyperparathyroidism.

AB - Human cryopreserved parathyroid autografts have been performed in six patients following reoperative parathyroid surgery. All patients were rendered hypoparathyroid by their most recent reoperation. Parathyroid tissue was successfully autotransplanted after as long as eighteen months of cryopreservation. Viability and expected in vivo function of cryopreserved parathyroid tissue may be predicted by in vitro testing of parathyroid hormone secretion in response to varying ambient calcium concentration. Parathyroid cryopreservation with subsequent autotransplantation is a practical solution to the problem of permanent hypoparathyroidism that may follow multiple surgical procedures for persistent hyperparathyroidism.

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Autotransplantation of cryopreserved parathyroid tissue in man

Abstract

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