Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

R. D. Jolly; K. E. Dittmer; B. R. Jones; A. J. Worth; K. G. Thompson; A. C. Johnstone; D. N. Palmer; N. S. Van de Water; K. M. Hemsley; D. J. Garrick; B. G. Winchester; S. U. Walkley

doi:10.1080/00480169.2021.1928564

Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

R. D. Jolly, K. E. Dittmer, B. R. Jones, A. J. Worth, K. G. Thompson, A. C. Johnstone, D. N. Palmer, N. S. Van de Water, K. M. Hemsley, D. J. Garrick, B. G. Winchester, S. U. Walkley

Neuroscience

Research output: Contribution to journal › Review article › peer-review

Abstract

Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.

Original language	English (US)
Pages (from-to)	255-266
Number of pages	12
Journal	New Zealand Veterinary Journal
Volume	69
Issue number	5
DOIs	https://doi.org/10.1080/00480169.2021.1928564
State	Published - 2021

Keywords

Genetic disorder
animal model
animals
genetic screening
lysosomal storage disease

ASJC Scopus subject areas

General Veterinary

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/00480169.2021.1928564

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Jolly, R. D., Dittmer, K. E., Jones, B. R., Worth, A. J., Thompson, K. G., Johnstone, A. C., Palmer, D. N., Van de Water, N. S., Hemsley, K. M., Garrick, D. J., Winchester, B. G., & Walkley, S. U. (2021). Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University. New Zealand Veterinary Journal, 69(5), 255-266. https://doi.org/10.1080/00480169.2021.1928564

Jolly, RD, Dittmer, KE, Jones, BR, Worth, AJ, Thompson, KG, Johnstone, AC, Palmer, DN, Van de Water, NS, Hemsley, KM, Garrick, DJ, Winchester, BG & Walkley, SU 2021, 'Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University', New Zealand Veterinary Journal, vol. 69, no. 5, pp. 255-266. https://doi.org/10.1080/00480169.2021.1928564

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abstract = "Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.",

keywords = "Genetic disorder, animal model, animals, genetic screening, lysosomal storage disease",

author = "Jolly, {R. D.} and Dittmer, {K. E.} and Jones, {B. R.} and Worth, {A. J.} and Thompson, {K. G.} and Johnstone, {A. C.} and Palmer, {D. N.} and {Van de Water}, {N. S.} and Hemsley, {K. M.} and Garrick, {D. J.} and Winchester, {B. G.} and Walkley, {S. U.}",

note = "Publisher Copyright: {\textcopyright} 2021 New Zealand Veterinary Association.",

year = "2021",

doi = "10.1080/00480169.2021.1928564",

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AU - Worth, A. J.

AU - Thompson, K. G.

AU - Johnstone, A. C.

AU - Palmer, D. N.

AU - Van de Water, N. S.

AU - Hemsley, K. M.

AU - Garrick, D. J.

AU - Winchester, B. G.

AU - Walkley, S. U.

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AB - Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.

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KW - animal model

KW - animals

KW - genetic screening

KW - lysosomal storage disease

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Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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