An OB's Guide to cord blood banking

Umbilical cord blood (UCB) is a valuable source of stem cells that can be used to treat a variety of diseases including hematological malignancies. Although UCB stem cells were once viewed as an alternative source of stem cells for therapeutic transplant, this readily available source has gained acceptance among transplant physicians and is now often considered as a first-line treatment. UCB conlams several classes of stem cells, including pluripotent forms, which offer promise in various emerging applications presently under preclinical and clinical investigation. Given both proven and nascent applications of UCB stem cells, expectant mothers should be educated about UCB options, including various banking options. There are essentially 3 options with regard to UCB - donating to a public bank, storing with a family bank, or discarding the UCB. Each option is associated with its own benefits and drawbacks. Obstetricians have the ability and opportunity to play an important role in this education. This article details the advances in UCB research and banking and provides useful information and tools for physicians to help educate expectant mothers and their families about UCB options.