Abstract
Using formalin-fixed, paraffin-embedded sections, indirect immunoperoxidase studies were performed on 3 autopsied and 1 biopsied cases of herpes simplex virus (HSV) encephalitis. Specific reaction was observed in all 4 cases. Distinct stain was observed both in neurons and in glial cells. Electron microscopic studies performed on the same material revealed HSV particles stained with electron-dense reaction products. The advantages and disadvantages of the use of formalin-fixed, paraffin embedded material in immunoperoxidase studies of viral disease are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 790-795 |
| Number of pages | 6 |
| Journal | Journal of Neuropathology and Experimental Neurology |
| Volume | 37 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 1978 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Neurology
- Clinical Neurology
- Cellular and Molecular Neuroscience