Abstract
Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. Exon skipping is the most commonly known alternative splicing mechanism. A comprehensive database of alternative splicing by exon skipping is made available for the human genome data. 1,229 human genes are identified to exhibit alternative splicing by exon skipping.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 221-225 |
| Number of pages | 5 |
| Journal | In Silico Biology |
| Volume | 5 |
| Issue number | 3 |
| State | Published - Aug 24 2005 |
Keywords
- Alternative splicing
- Computational analysis
- Database
- Eukaryotic gene structure
- Exon skipping
- Full length cDNA sequences
- Genome wide splicing
- Multiple splice variants
- Protein diversity
- Protein isoforms
- Skipping patterns
- Tissue specificity
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Computational Mathematics
- Computational Theory and Mathematics