All Talk, No Assembly: Voltage-Gated Calcium Channels Do Not Mediate Active Zone Formation

Elisa B. Frankel; Peri T. Kurshan

doi:10.1016/j.neuron.2020.07.028

All Talk, No Assembly: Voltage-Gated Calcium Channels Do Not Mediate Active Zone Formation

Elisa B. Frankel, Peri T. Kurshan

Neuroscience

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

How synapses assemble remains unknown. In this issue of Neuron, Held et al. (2020) demonstrate that Ca_v2-type voltage-gated calcium channels do not mediate presynaptic assembly. Moreover, the channel-associated protein α2δ localizes independently, suggesting additional functions for this auxiliary protein.

Original language	English (US)
Pages (from-to)	593-594
Number of pages	2
Journal	Neuron
Volume	107
Issue number	4
DOIs	https://doi.org/10.1016/j.neuron.2020.07.028
State	Published - Aug 19 2020

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neuron.2020.07.028

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title = "All Talk, No Assembly: Voltage-Gated Calcium Channels Do Not Mediate Active Zone Formation",

abstract = "How synapses assemble remains unknown. In this issue of Neuron, Held et al. (2020) demonstrate that Cav2-type voltage-gated calcium channels do not mediate presynaptic assembly. Moreover, the channel-associated protein α2δ localizes independently, suggesting additional functions for this auxiliary protein.",

author = "Frankel, {Elisa B.} and Kurshan, {Peri T.}",

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AU - Kurshan, Peri T.

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AB - How synapses assemble remains unknown. In this issue of Neuron, Held et al. (2020) demonstrate that Cav2-type voltage-gated calcium channels do not mediate presynaptic assembly. Moreover, the channel-associated protein α2δ localizes independently, suggesting additional functions for this auxiliary protein.

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All Talk, No Assembly: Voltage-Gated Calcium Channels Do Not Mediate Active Zone Formation

Abstract

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