Abstract
Immune thrombocytopenia (ITP) is a bleeding disorder characterized by immune-mediated platelet destruction and resultant thrombocytopenia. Newly diagnosed ITP denotes those within the first 3 months of diagnosis, persistent ITP refers to those between 3 months and 1 year of diagnosis, and chronic ITP represents more than 1 year of disease persistence. Persistent ITP that resolves within 1 year occurs almost exclusively in children and is one of the most common acquired bleeding disorders in the pediatric population, with an estimated prevalence of 4-8 per 100,000 children per year. In contrast, most adults who present with ITP develop chronic disease, and spontaneous recovery occurs in less than 10% of such cases. Acute and chronic ITP are approached differently; acute childhood ITP will be reviewed in this chapter, whereas chronic ITP is presented in Chapter 116.
Original language | English (US) |
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Title of host publication | Transfusion Medicine and Hemostasis |
Subtitle of host publication | Clinical and Laboratory Aspects |
Publisher | Elsevier |
Pages | 515-518 |
Number of pages | 4 |
ISBN (Electronic) | 9780323960144 |
ISBN (Print) | 9780323960151 |
DOIs | |
State | Published - Jan 1 2024 |
Keywords
- Acute
- Childhood
- ITP
- IVIG
- Steroids
- Thrombocytopenia
- Winrho
ASJC Scopus subject areas
- General Medicine