Acute (Childhood) Immune Thrombocytopenia

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Immune thrombocytopenia (ITP) is a bleeding disorder characterized by immune-mediated platelet destruction and resultant thrombocytopenia. Newly diagnosed ITP denotes those within the first 3 months of diagnosis, persistent ITP refers to those between 3 months and 1 year of diagnosis, and chronic ITP represents more than 1 year of disease persistence. Persistent ITP that resolves within 1 year occurs almost exclusively in children and is one of the most common acquired bleeding disorders in the pediatric population, with an estimated prevalence of 4-8 per 100,000 children per year. In contrast, most adults who present with ITP develop chronic disease, and spontaneous recovery occurs in less than 10% of such cases. Acute and chronic ITP are approached differently; acute childhood ITP will be reviewed in this chapter, whereas chronic ITP is presented in Chapter 116.

Original languageEnglish (US)
Title of host publicationTransfusion Medicine and Hemostasis
Subtitle of host publicationClinical and Laboratory Aspects
PublisherElsevier
Pages515-518
Number of pages4
ISBN (Electronic)9780323960144
ISBN (Print)9780323960151
DOIs
StatePublished - Jan 1 2024

Keywords

  • Acute
  • Childhood
  • ITP
  • IVIG
  • Steroids
  • Thrombocytopenia
  • Winrho

ASJC Scopus subject areas

  • General Medicine

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