193 nm excimer laser-induced fluorescence spectroscopy during corneal ablative surgery

Roy S. Chuck, David Cohen, Peter J. McDonnell, Warren S. Grundfest

Research output: Contribution to journalConference articlepeer-review


The evolution of real-time laser-induced fluorescence at progressive corneal depths detected during excimer laser corneal ablative surgery at 193 nm excitation was investigated using an 8.5 mm corneal button trephined from a fresh frozen cadaveric human globe, and placed in the ablative 192 nm excimer laser beam path. The spectra of the initial epithelial ablation - consecutive spectra taken in the anterior to mid-stroma after lamellar keratomileusis and subsequent laser ablation, and the initial spectrum taken while ablating from the endothelial side was demonstrated. A striking progression of the spectra was observed as ablation progresses from the epithelial side towards the endothelial side.

Original languageEnglish (US)
Pages (from-to)218-219
Number of pages2
JournalConference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS
StatePublished - 1999
Externally publishedYes
EventProceedings of the 1999 12th Annual Meeting IEEE Lasers and Electro-Optics Society (LEOS'99) - San Francisco, CA, USA
Duration: Nov 8 1999Nov 11 1999

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering


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