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Transition State Analogues as Modulators of DNA Methylation
Schramm, Vern L.
(PI)
Rose, Susan A.
(PI)
Rose, Susan A.
(PI)
Biochemistry
Pediatrics
Project
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Medicine & Life Sciences
1-(9-deazaadenin-9-yl)methyl-3-hydroxy-4-methylthiomethylpyrrolidine
23%
5'-methylthioadenosine phosphorylase
100%
Breast
7%
Cell Division
8%
Cell Extracts
10%
Cell Line
5%
Colon
7%
CpG Islands
34%
Cultured Cells
23%
DNA
26%
DNA Methylation
46%
Enzymes
5%
Gene Expression
28%
Genome
6%
Growth
19%
Head
6%
Head and Neck Neoplasms
9%
Heterografts
25%
Lung
5%
Lung Neoplasms
7%
Methylation
8%
Methyltransferases
31%
Mutation
5%
Neck
7%
Neoplasm Genes
10%
Neoplasm Metastasis
5%
Neoplasms
39%
Pharmaceutical Preparations
11%
Prostate
15%
Technology
6%
Uterine Cervical Neoplasms
8%