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Keyphrases
Structure Function
100%
Disease-causing mutations
100%
Connexin
100%
Connexin 26
100%
Cx32
100%
Connexin Channels
60%
Channel Function
43%
Plasma Membrane
40%
Hemichannel
40%
Cause of Disease
40%
All-atom Molecular Dynamics Simulation
40%
Permselectivity
40%
Atomic Model
40%
Effective Treatment
24%
Nonsyndromic Deafness
24%
X-linked
24%
Syndromic Deafness
24%
Homology Modeling
20%
Biogenesis
20%
Canine
20%
Molecular Mechanism
20%
X-ray Crystallography
20%
Testable Hypothesis
20%
Channel Structure
20%
Amino Acid Substitution
20%
2D NMR
20%
Mutational Target
20%
Second Messenger
20%
Membrane Insertion
20%
Mutant Peptide
20%
Experimental Strategies
20%
Biophysical Characterization
20%
Disease Class
20%
Microsomal Membranes
20%
Membrane Environment
20%
Molecular Defects
20%
Structural Determination
20%
Method Characterization
20%
Sensitive Test
20%
3D NMR
20%
Charcot-Marie-Tooth
20%
Voltage Gating
20%
Disease Etiology
20%
Structural Solutions
20%
Computational Methods
20%
Structural Defects
20%
N-terminal Domain
20%
Inherited Disease
20%
Computational Study
20%
Oligomerization
20%
Open Channel
20%
Biochemistry, Genetics and Molecular Biology
Connexin
100%
Structure Activity Relation
100%
Wild Type
27%
Cell Membrane
27%
Dynamics
27%
Anabolism
15%
Solution and Solubility
13%
Genetic Disorder
13%
Amino Acid Substitution
13%
Crystallography
13%
Electric Potential
13%
Crystal Structure
13%
Microsome Membrane
13%
N-Terminus
13%
Second Messenger System
13%
Oligomerization
13%
Biogenesis
13%