• Spiegel, Allen M. (PI)
  • Purpura, D. P. (CoPI)
  • Spiegel, Allen M. (CoPI)
  • Howard, Andrea A.A (CoPI)
  • Melman, Arnold (CoPI)
  • Bloom, Barry R. (CoPI)
  • Diamond, Betty B (CoPI)
  • Segal-isaacson, Cj C (CoPI)
  • Stein, Daniel D.C (CoPI)
  • Schoenbaum, Ellie (CoPI)
  • Kaskel, Frederick J. (CoPI)
  • Ho, Gloria Yuen Fun (CoPI)
  • Shamoon, Harry H (CoPI)
  • Hetherington, H. P. (CoPI)
  • Crystal, H. (CoPI)
  • Roy-chowdhury, Jayanta J (CoPI)
  • Pollard, Jeffrey J.W (CoPI)
  • Rieder, Jessica (CoPI)
  • Crandall, Jill P. (CoPI)
  • Wylie-rosett, Judith J (CoPI)
  • Pan, Jullie J.W (CoPI)
  • Rossetti, L. (CoPI)
  • Weiss, Louis L.M (CoPI)
  • Bigal, M. (CoPI)
  • Hawkins, Meredith A. (CoPI)
  • Brownlee, Michael M.A (CoPI)
  • Alderman, M. H. (CoPI)
  • Schilsky, M. L. (CoPI)
  • Fabry, Mary M.E (CoPI)
  • Roy-Chowdhury, Namita (CoPI)
  • Barzilai, Nir (CoPI)
  • Fleischer, Norman (CoPI)
  • Santoro, Nanette N.F (CoPI)
  • Kennan, Richard P. (CoPI)
  • Bookchin, R. (CoPI)
  • Klein, Robert R.M (CoPI)
  • Lipton, Richard B. (CoPI)
  • Burk, Robert R.D (CoPI)
  • Nagel, R. L. (CoPI)
  • Engel, Samuel S.S (CoPI)
  • Gupta, Sanjeev S (CoPI)
  • Somlo, Stefan S (CoPI)
  • Berk, Steven Ira (CoPI)
  • Weber, Thomas T.J (CoPI)
  • Frishman, W. H. (CoPI)
  • Noyer, C. M. (CoPI)
  • Barzilai, Nir J. (CoPI)
  • Burk, Robert D. (CoPI)
  • Fabry, Mary E. (CoPI)
  • Fleischer, Norman S. (CoPI)
  • Hawkins, Meredith A. (CoPI)
  • Ho, Gloria Yf (CoPI)
  • Kaufman, Howard H.H (CoPI)
  • Nagel, Ronald L. (CoPI)
  • Rubenstein, Arye A (CoPI)
  • Santoro, Nanette F. (CoPI)
  • Schilsky, Michael L. (CoPI)
  • Stein, Daniel T. (CoPI)
  • Wadler, Scott H. (CoPI)
  • Wozniak, Robert (CoPI)

Project: Research project

Project Details


The Einstein-Montefiore GCRC has benefited from the augmentation of clinical research nationally as well as[unreadable] from Institutional investments that have permitted expansion in its scope and innovation. Our per diem GCRC[unreadable] provides platforms and tools to sustain a diverse portfolio of research spanning diabetes, epilepsy, aging, and[unreadable] reproductive physiology, to sickle cell anemia, HIV/AIDS, CVD, and cancer. In our current project period, we[unreadable] successfully implemented 2 state-of-the-art Cores, one a high-field Magnetic Resonance (MR) Research Core,[unreadable] and the second an Analytic Core Laboratory providing mass spectrometry and other analyses. Our training[unreadable] efforts have not only yielded new K12 and K23 investigators who use the GCRC for their projects, but have[unreadable] also integrated the GCRC with the training mission of the College of Medicine. The GAC and the RSA have[unreadable] collaborated with the IRBs to put data and safety monitoring guidelines into practice, and we have implemented[unreadable] secure research informatics management. In the aggregate, the GCRC has experienced dramatic outpatient visit[unreadable] increases in the past two years, and our investigators have been highly productive; thus, the current application[unreadable] includes 60 projects, -50% more than in our previous application with a total of over $55 million in Federal[unreadable] research grant support. The Principal Investigator of the GCRC is Dominick Purpura, MD, Dean of the College[unreadable] of Medicine, and its Program Director is Harry Shamoon, MD, Associate Dean for Clinical Research. Drs.[unreadable] Ronald Nagel and Sanjeev Gupta will continue as Associate Program Directors. Jullie Pan MD, PhD and Daniel[unreadable] Stein, MD are directors of the MR and the Analytic Cores, respectively, and Hillel Cohen, DrPH continues as[unreadable] GCRC Biostatistician. Margaret Arnim, MBA is the Administrative Director. Owing to the success of our[unreadable] GCRC in supporting clinical investigation, the Institution is completing a second outpatient GCRC facility and[unreadable] laboratory adjacent to the new Children's Hospital at Montefiore that will increase capacity and provide a[unreadable] (heretofore unavailable) site for pediatric clinical research. The GCRC is at the focal point of the Institution's[unreadable] Strategic Plan for clinical and translational research that includes constructing a $200-million Center for Genetic[unreadable] and Translational Medicine, recruiting clinical investigators, developing innovative research training and career[unreadable] development, and facilitating new scientific endeavors. Based on our track record, we hope this application[unreadable] demonstrates that our GCRC merits further investment. In keeping with growth of the Center, we request[unreadable] support for an expanded leadership including Associate Program Directors for Pediatrics (Frederick Kaskel[unreadable] MD,PhD), Research Training (Paul Marantz MD,MPH), and Neurology (Shlomo Shinnar MD,PhD), and also[unreadable] for the additional personnel and resources to enable this much-needed expansion.
Effective start/end date9/30/9711/30/97


  • National Center for Research Resources: $739,304.00
  • National Center for Research Resources: $2,536,608.00


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