DIABETES RESEARCH AND TRAINING CENTER

This proposal is to continue funding of the Einstein/Montefiore Diabetes
Research and Training Center. We propose to provide vital research support
to funded diabetes investigation throughout the continuance of 4 core
biomedical research laboratories. These four laboratories,
radioimmunoassay-islet, cell culture, chemical and high pressure liquid
chromatography will provide consulltation and determinations of islet
hormones, glucose, lipids, lipoproteins and liquid chromatography. These
labs will provide several cell lines, rat pancreatic islets and assistance
in polypeptide receptor binding studies. The DRTC will provide a
feasibility study mechanism by which faculty may obtain pilot funds for new
directions in research, such as; the electrophysiology of islets,
antibody-mediated placental hormone transport, factors involved in glycemic
control, diabetes effects on isolated heart cells, lipoprotein binding to
liver cells, phospholipid turnover in beta cells, parasitic infections in
experimental diabetes, genetic basis for susceptibility to diabetes and
psychosocial determinants of glycemic control. The DTRC will continue its
commitment to health provider education through its Diabetes Education Team
to design, evaluate and utilize a series of educational strategies. The
Center activities will be supported by a computer laboratory, an enrichment
program and by an administrative structure that includes the principals
involved in all its activities, and both internal and external advisory
committees. The overall goal is to improve care to diabetics by fostering
research and education in diabetes.