Projects per year
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Dive into the research topics where Wenjun Guo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Grants
- 7 Finished
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Targeting lineage plasticity to inhibit basal-like breast cancer progression
Guo, W. (PI)
1/1/25 → 12/31/25
Project: Research project
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The Biology of Lung Metastasis in Breast Cancer
Backer, J. M. (PI), Bresnick, A. A. R. (CoPI), Entenberg, D. R. (CoPI), Oktay, M. H. (CoPI), Porcelli, S. A. (CoPI) & Guo, W. (CoPI)
7/5/22 → 6/30/23
Project: Research project
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Role of SOX9 mammary stem cell factor in metastasis
Guo, W. (PI)
6/1/22 → 5/31/23
Project: Research project
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Role of the histone modifier MLL3 mutation in breast cancer cell plasticity
Guo, W. (PI)
3/1/20 → 2/28/22
Project: Research project
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Role of the histone modifier MLL3 mutation in breast cancer cell plasticity
Guo, W. (PI)
3/1/20 → 2/28/25
Project: Research project
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Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells
Boutet, M., Nishitani, K., Couturier, N., Erler, P., Zhang, Z., Militello, A. M., Coutinho De Miranda, M., Barbieux, E., Guillen, E., Leavenworth, J. W., Suzuki, M., Sparano, J. A., Lu, J., Fineberg, S. A., Wang, Y., Mani, S. A., Montagna, C., Guo, W. & Lauvau, G., Aug 12 2025, In: Immunity. 58, 8, p. 2035-2053.e9Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
Liu, Y., John, P., Nishitani, K., Cui, J., Nishimura, C. D., Christin, J. R., Couturier, N., Ren, X., Wei, Y., Pulanco, M. C., Galbo, P. M., Zhang, X., Fu, W., Cui, W., Bartholdy, B. A., Zheng, D., Lauvau, G., Fineberg, S. A., Oktay, M. H. & Zang, X. & 1 others, , Dec 4 2023, In: Developmental cell. 58, 23, p. 2700-2717.e12Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
MLL3 loss drives metastasis by promoting a hybrid epithelial–mesenchymal transition state
Cui, J., Zhang, C., Lee, J. E., Bartholdy, B. A., Yang, D., Liu, Y., Erler, P., Galbo, P. M., Hodge, D. Q., Huangfu, D., Zheng, D., Ge, K. & Guo, W., Jan 2023, In: Nature Cell Biology. 25, 1, p. 145-158 14 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Targeting ABCA12-controlled ceramide homeostasis inhibits breast cancer stem cell function and chemoresistance
Cui, J., Christin, J. R., Reisz, J. A., Cendali, F. I., Sanawar, R., De Miranda, M. C., D'Alessandro, A. & Guo, W., Dec 2023, In: Science Advances. 9, 48, eadh1891.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Establishment and long-term culture of mouse mammary stem cell organoids and breast tumor organoids
Cui, J. & Guo, W., Jun 18 2021, In: STAR Protocols. 2, 2, 100577.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations