Projects per year
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Collaborations and top research areas from the last five years
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Cancer Center Support Grant
Almo, S. C. (CoPI), Hogue-Angeletti, R. (CoPI), Augenlicht, L. H. (CoPI), Condeelis, J. S. (CoPI), Desai, K. (CoPI), Edelmann, W. (CoPI), Goldman, I. D. (CoPI), Greally, J. M. (CoPI), Herbst, L. H. (CoPI), Keller, S. M. (CoPI), Kim, M. Y. (CoPI), Mahmood, R. (CoPI), Montagna, C. (CoPI), Morrow, B. E. (CoPI), Pollard, J. W. (CoPI), Porcelli, S. A. (CoPI), Rohan, T. E. (CoPI), Scharff, M. D. (CoPI), Seither, R. (CoPI), Skoultchi, A. I. (CoPI), Sparano, J. A. (CoPI), Stanley, P. M. (CoPI), Chu, E. E. (PI), Bresnick, A. R. (CoPI), Skoultchi, A. I. (CoPI), Adedimeji, A. A. (CoPI), Beck, A. A. P. (CoPI), Blanchard, J. S. (CoPI), Halmos, B. B. (CoPI), Morrow, B. E. (CoPI), Diamond, B. B. (CoPI), Will, B. B. (CoPI), Rapkin, B. D. (CoPI), Chu, E. (CoPI), Montagna, C. C. (CoPI), Stein, D. T. (CoPI), Gaertner, D. D. J. (CoPI), Chu, E. E. (CoPI), Ho, G. Y. (CoPI), Goel, S. (CoPI), Hosgood, H. D. H. (CoPI), Strickler, H. H. D. (CoPI), Pollard, J. J. W. (CoPI), Condeelis, J. J. S. (CoPI), Dutcher, J. J. P. (CoPI), Greally, J. J. (CoPI), Backer, J. M. (CoPI), Sparano, J. J. A. (CoPI), Maianti, J. P. (CoPI), Aguirre-ghiso, J. J. A. (CoPI), Gritsman, K. K. (CoPI), Herbst, L. H. (CoPI), Augenlicht, L. H. (CoPI), Cannizzaro, L. A. (CoPI), Hackett, L. L. E. (CoPI), Scharff, M. M. D. (CoPI), Brenowitz, M. D. (CoPI), Kim, M. (CoPI), Ohri, N. N. (CoPI), Stanley, P. (CoPI), Gupta, R. R. K. (CoPI), Depinho, R. R. A. (CoPI), Kucherlapati, R. R. S. (CoPI), Schramm, V. L. (CoPI), Keller, S. M. (CoPI), Almo, S. C. (CoPI), Porcelli, S. S. A. (CoPI), Rohan, T. E. (CoPI), Steidl, U. U. G. (CoPI), Edelmann, W. (CoPI), Xue, X. X. N. (CoPI), Alderman, M. H. (CoPI), Atkinson, P. H. (CoPI), Bases, R. E. (CoPI), Birshstein, B. K. (CoPI), Bloom, B. R. (CoPI), Blumenfeld, O. O. (CoPI), Brenowitz, M. D. (CoPI), Brewer, F. C. (CoPI), Buhl, S. (CoPI), Chance, M. R. (CoPI), Chase, J. W. (CoPI), Childs, G. J. (CoPI), Depinho, R. (CoPI), Depinho, R. A. (CoPI), Duran-reynals, M. L. (CoPI), Dutcher, J. P. (CoPI), Eagle, H. (CoPI), Fant, J. (CoPI), Gaertner, D. J. (CoPI), Grills, G. (CoPI), Gupta, R. K. (CoPI), Horwitz, S. B. (CoPI), Horwitz, M. S. (CoPI), Hurwitz, J. (CoPI), Kadish, A. S. (CoPI), Klinger, H. P. (CoPI), Krauter, K. S. (CoPI), Kucherlapati, R. S. (CoPI), Levine, W. G. (CoPI), Lilly, F. (CoPI), Maio, J. J. (CoPI), Maitra, U. (CoPI), Makman, M. H. (CoPI), Marians, K. J. (CoPI), Nathenson, S. G. (CoPI), Orr, G. A. (CoPI), Peisach, J. (CoPI), Pickering, K. (CoPI), Rajan, T. V. (CoPI), Reid, L. M. (CoPI), Rubin, C. S. (CoPI), Russel, R. (CoPI), Satir, B. H. (CoPI), Schildkraut, C. L. (CoPI), Schulman, L. H. (CoPI), Serrano, L. J. (CoPI), Shapiro, L. (CoPI), Shin, S.-I. (CoPI), Wadler, S. H. (CoPI), Warner, J. R. (CoPI), West, M. (CoPI) & Wiernik, P. H. (CoPI)
6/1/85 → 6/30/26
Project: Research project
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The Unexpected Role of TNFRSF14 Signaling in Promoting Antibody-Dependent Cell-Mediated Cytotoxicity
Herold, B. (PI) & Almo, S. C. (CoPI)
National Institute of Allergy and Infectious Diseases
11/7/24 → 10/31/25
Project: Research project
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Amplifying and Redirecting CMV-specific CD8 T cells to provide sustained control of HIV infection
Goldstein, H. (PI) & Almo, S. C. (PI)
6/3/22 → 5/31/23
Project: Research project
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Novel Strategies for the Discovery of Microbial Metabolic Pathways
Almo, S. C. (PI)
5/1/20 → 4/30/21
Project: Research project
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Design of high-affinity binders to immune modulating receptors for cancer immunotherapy
Yang, W., Hicks, D. R., Ghosh, A., Schwartze, T. A., Conventry, B., Goreshnik, I., Allen, A., Halabiya, S. F., Kim, C. J., Hinck, C. S., Lee, D. S., Bera, A. K., Li, Z., Wang, Y., Schlichthaerle, T., Cao, L., Huang, B., Garrett, S., Gerben, S. R. & Rettie, S. & 8 others, , Dec 2025, In: Nature communications. 16, 1, 2001.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
T-cell receptor/CD28-targeted immunotherapeutics selectively drive naive T-cell expansion to generate functional HIV-specific responses
Mueller, A. L., Lamcaj, S., Garforth, S., Hiner, C., Woodley, D., Paraiso, K., Mi, T., Low, S., Youngblood, B., Almo, S. C. & Goldstein, H., Sep 2025, In: Journal of virology. 99, 9Research output: Contribution to journal › Article › peer-review
Open Access -
Transition State Analogs of Human DNPH1 Reveal Two Electrophile Migration Mechanisms
Wagner, A. G., Lang, T. B. D., Ledingham, E. T., Ghosh, A., Brooks, D., Eskandari, R., Suthagar, K., Almo, S. C., Lamiable-Oulaidi, F., Tyler, P. C. & Schramm, V. L., Feb 13 2025, In: Journal of Medicinal Chemistry. 68, 3, p. 3653-3672 20 p.Research output: Contribution to journal › Article › peer-review
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Unique mechanisms to increase structural stability and enhance antigen binding in nanobodies
Ketaren, N. E., Fridy, P. C., Malashkevich, V., Sanyal, T., Brillantes, M., Thompson, M. K., Oren, D. A., Bonanno, J. B., Šali, A., Almo, S. C., Chait, B. T. & Rout, M. P., Apr 3 2025, In: Structure. 33, 4, p. 677-690.e5Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria
Grosjean, N., Yee, E. F., Kumaran, D., Chopra, K., Abernathy, M., Biswas, S., Byrnes, J., Kreitler, D. F., Cheng, J. F., Ghosh, A., Almo, S. C., Iwai, M., Niyogi, K. K., Pakrasi, H. B., Sarangi, R., van Dam, H., Yang, L., Blaby, I. K. & Blaby-Haas, C. E., Dec 2024, In: Nature communications. 15, 1, 3167.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations