Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- RZ Other systems of medicine
- Microbiome
- Health
- orphan nuclear receptors
- inflammatory bowel disease
- colon cancer
- probiotics
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Collaborations and top research areas from the last five years
Grants
- 11 Finished
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Developmental PBDE exposure, gut microbiome, and diabetes
Mani, S. (CoPI)
1/1/19 → 12/31/21
Project: Research project
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Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer
Mani, S. (PI)
8/14/18 → 7/31/21
Project: Research project
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Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer
Mani, S. (PI) & Mani, S. (CoPI)
8/14/18 → 7/31/23
Project: Research project
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Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer
Mani, S. (PI)
8/14/18 → 7/31/22
Project: Research project
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Development of Novel Drugs to Alleviate CPT-11 Toxicity
Mani, S. (PI), Redinbo, M. (PI), Rose, S. A. (PI), Rose, S. A. (PI), Rose, S. A. (PI), Rose, S. A. (PI) & Rose, S. A. (PI)
4/1/12 → 3/31/18
Project: Research project
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An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice
Wang, X., Zhang, G., Bian, Z., Chow, V., Grimaldi, M., Carivenc, C., Sirounian, S., Li, H., Sladekova, L., Stefano, M., Luperi, Y., Gong, Y., Costello, C., Li, L., Jachimowicz, M., Guo, M., Hu, S., Wilson, D., Balaguer, P. & Bourguet, W. & 8 others, , Dec 2025, In: Nature communications. 16, 1, 1280.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Correction to: An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice (Nature Communications, (2025), 16, 1, (1280), 10.1038/s41467-025-56624-0)
Wang, X., Zhang, G., Bian, Z., Chow, V., Grimaldi, M., Carivenc, C., Sirounian, S., Li, H., Sladekova, L., Motta, S., Luperi, Y., Gong, Y., Costello, C., Li, L., Jachimowicz, M., Guo, M., Hu, S., Wilson, D., Balaguer, P. & Bourguet, W. & 8 others, , Dec 2025, In: Nature communications. 16, 1, 2133.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Decoding structural determinants of aryl hydrocarbon receptor antagonism by monoterpenoids
Zůvalová, I., Vyhlídalová, B., Ondrová, K., Nádvorník, P., Hrubý, J., Illés, P., Soural, M., Šebela, M., Šindlerová, L., Kubala, L., Mani, S. & Dvořák, Z., Apr 2025, In: Bioorganic Chemistry. 157, 108265.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Deep learning-based detection of bacterial swarm motion using a single image
Li, Y., Li, H., Chen, W., O’Riordan, K., Mani, N., Qi, Y., Liu, T., Mani, S. & Ozcan, A., 2025, In: Gut Microbes. 17, 1, 2505115.Research output: Contribution to journal › Article › peer-review
Open Access -
Emerging approaches for antagonizing the aryl hydrocarbon receptor
Dvořák, Z., Mani, S. & Vondráček, J., Jul 2025, In: Trends in Pharmacological Sciences. 46, 7, p. 629-637 9 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations