Projects per year
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Dive into the research topics where Matthew J. Gamble is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Grants
- 6 Finished
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Determination of genome-wide splicing kinetics and their underlying regulation
Gamble, M. J. (PI)
4/1/20 → 3/31/22
Project: Research project
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Determination of genome-wide splicing kinetics and their underlying regulation
Gamble, M. J. (PI)
National Institute of General Medical Sciences
4/1/20 → 3/31/24
Project: Research project
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The role of macroH2A variants in cancer and senescence
Gamble, M. J. (PI), Rose, S. A. (PI) & Rose, S. A. (PI)
5/4/12 → 3/31/22
Project: Research project
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The role of macroH2A variants in cancer and senescence
Gamble, M. J. (PI) & Gamble, M. J. (CoPI)
5/4/12 → 3/31/22
Project: Research project
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Role of MacroH2A in Estrogen-Regulated Gene Expression
Gamble, M. J. (PI) & Rose, S. A. (PI)
3/5/08 → 7/31/09
Project: Research project
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Productive mRNA chromatin escape is promoted by PRMT5 activity
DeAngelo, J. D., Maron, M. I., Roth, J. S., Hegde, S., Silverstein, A. M., Gupta, V., Stransky, S., Basken, J., Azofeifa, J., Query, C. C., Sidoli, S., Gamble, M. J. & Shechter, D., Nov 6 2025, In: Molecular Cell. 85, 21, p. 4016-4031.e9Research output: Contribution to journal › Article › peer-review
Open Access -
Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation
Maron, M. I., Casill, A. D., Gupta, V., Roth, J. S., Sidoli, S., Query, C. C., Gamble, M. J. & Shechter, D., Jan 2022, In: eLife. 11, e72867.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
MacroH2A1.1 has evolved to let PARP1 do more by loosening its grip on PAR
Hamilton, G. A. & Gamble, M. J., Dec 2021, In: Nature Structural and Molecular Biology. 28, 12, p. 961-962 2 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction
Healton, S. E., Pinto, H. D., Mishra, L. N., Hamilton, G. A., Hamilton, G. A., Wheat, J. C., Swist-Rosowska, K., Shukeir, N., Dou, Y., Steidl, U., Jenuwein, T., Gamble, M. J., Gamble, M. J. & Skoultchi, A. I., Jun 23 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 25, p. 14251-14258 8 p.Research output: Contribution to journal › Article › peer-review
Open Access65 Scopus citations -
MacroH2A1 regulation of poly (ADP-Ribose) synthesis and stability prevents necrosis and promotes DNA repair
Ruiz, P. D., Hamilton, G. A., Park, J. W. & Gamble, M. J., Jan 1 2020, In: Molecular and cellular biology. 40, 1, e00230-19.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations