Projects per year
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Collaborations and top research areas from the last five years
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Cancer Center Support Grant
Almo, S. C. (CoPI), Hogue-Angeletti, R. (CoPI), Augenlicht, L. H. (CoPI), Condeelis, J. S. (CoPI), Desai, K. (CoPI), Edelmann, W. (CoPI), Goldman, I. D. (CoPI), Greally, J. M. (CoPI), Herbst, L. H. (CoPI), Keller, S. M. (CoPI), Kim, M. Y. (CoPI), Mahmood, R. (CoPI), Montagna, C. (CoPI), Morrow, B. E. (CoPI), Pollard, J. W. (CoPI), Porcelli, S. A. (CoPI), Rohan, T. E. (CoPI), Scharff, M. D. (CoPI), Seither, R. (CoPI), Skoultchi, A. I. (CoPI), Sparano, J. A. (CoPI), Stanley, P. M. (CoPI), Steidl, U. U. (PI), Bresnick, A. R. (CoPI), Skoultchi, A. I. (CoPI), Adedimeji, A. A. (CoPI), Beck, A. A. P. (CoPI), Morrow, B. E. (CoPI), Blanchard, J. S. (CoPI), Halmos, B. B. (CoPI), Morrow, B. B. (CoPI), Diamond, B. B. (CoPI), Will, B. B. (CoPI), Rapkin, B. D. (CoPI), Chu, E. (CoPI), Montagna, C. C. (CoPI), Stein, D. T. (CoPI), Gaertner, D. D. J. (CoPI), Ho, G. Y. (CoPI), Goel, S. (CoPI), Hosgood, H. D. H. (CoPI), Strickler, H. H. D. (CoPI), Pollard, J. J. W. (CoPI), Dutcher, J. J. P. (CoPI), Backer, J. M. (CoPI), Sparano, J. J. A. (CoPI), Maianti, J. P. (CoPI), Aguirre-ghiso, J. J. A. (CoPI), Gritsman, K. K. (CoPI), Cannizzaro, L. A. (CoPI), Hackett, L. L. E. (CoPI), Scharff, M. M. D. (CoPI), Brenowitz, M. D. (CoPI), Ohri, N. N. (CoPI), Stanley, P. (CoPI), Gupta, R. R. K. (CoPI), Depinho, R. R. A. (CoPI), Kucherlapati, R. (CoPI), Schramm, V. L. (CoPI), Steidl, U. G. (CoPI), Almo, S. C. (CoPI), Xue, X. X. N. (CoPI), Alderman, M. H. (CoPI), Atkinson, P. H. (CoPI), Bases, R. E. (CoPI), Birshstein, B. K. (CoPI), Bloom, B. R. (CoPI), Blumenfeld, O. O. (CoPI), Brenowitz, M. D. (CoPI), Brewer, F. C. (CoPI), Buhl, S. (CoPI), Chance, M. R. (CoPI), Chase, J. W. (CoPI), Childs, G. J. (CoPI), Depinho, R. (CoPI), Depinho, R. A. (CoPI), Duran-reynals, M. L. (CoPI), Dutcher, J. P. (CoPI), Eagle, H. (CoPI), Fant, J. (CoPI), Gaertner, D. J. (CoPI), Grills, G. (CoPI), Gupta, R. K. (CoPI), Horwitz, S. B. (CoPI), Horwitz, M. S. (CoPI), Hurwitz, J. (CoPI), Kadish, A. S. (CoPI), Klinger, H. P. (CoPI), Krauter, K. S. (CoPI), Kucherlapati, R. S. (CoPI), Levine, W. G. (CoPI), Lilly, F. (CoPI), Maio, J. J. (CoPI), Maitra, U. (CoPI), Makman, M. H. (CoPI), Marians, K. J. (CoPI), Nathenson, S. G. (CoPI), Orr, G. A. (CoPI), Peisach, J. (CoPI), Pickering, K. (CoPI), Rajan, T. V. (CoPI), Reid, L. M. (CoPI), Rubin, C. S. (CoPI), Russel, R. (CoPI), Satir, B. H. (CoPI), Schildkraut, C. L. (CoPI), Schulman, L. H. (CoPI), Serrano, L. J. (CoPI), Shapiro, L. (CoPI), Shin, S.-I. (CoPI), Wadler, S. H. (CoPI), Warner, J. R. (CoPI), West, M. (CoPI), Wiernik, P. H. (CoPI) & Diamond, B. (CoPI)
6/1/85 → 6/30/27
Project: Research project
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Prevention and Therapy of Inflammation Associated Colorectal Cancer
Augenlicht, L. H. (PI)
1/1/25 → 12/31/25
Project: Research project
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A Major Nutritional Effect on Intestinal Stem Cells and Tumors
Augenlicht, L. H. (PI)
7/17/18 → 5/31/21
Project: Research project
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A Major Nutritional Effect on Intestinal Stem Cells and Tumors
Augenlicht, L. L. H. (PI) & Augenlicht, L. H. (CoPI)
7/17/18 → 5/31/23
Project: Research project
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High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer
Thielen, N., Wei, N., Nagai, E., Houston, M., Augenlicht, L. H., Shin, A. E., Gabre, J. T., Rustgi, A. K., Ha, G., LaFave, L. M., Chu, E., Kitamura, S. & Kuang, C., Dec 2026, In: npj Precision Oncology. 10, 1, 211.Research output: Contribution to journal › Article › peer-review
Open Access -
TNFR1 signaling connects inflammation to impaired fatty acid oxidation to drive intestinal stem cell aging
Wang, R., Tabrizian, T., Wang, D., English, J., Ayer, A., Gal, M., Yang, W.-L., Wu, Z., Mao, K., Novaj, A., Zhang, X., Basu, I., Brodin, N. P., Koba, W. R., Saxena, D., Choi, J., Augenlicht, L. H., Ericsson, A., Gavathiotis, E. & Guha, C. & 1 others, , Aug 2026, In: Nature Aging. 6, 8, p. 1631-1646 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition
Bedard, G. T., Gilaj, N., Peregrina, K., Brew, I., Tosti, E., Shaffer, K., Tyler, P. C., Edelmann, W., Augenlicht, L. H. & Schramm, V. L., Jan 2024, In: Journal of Biological Chemistry. 300, 1, 105492.Research output: Contribution to journal › Article › peer-review
Open Access39 Link opens in a new tab Scopus citations -
Intestinal stem cells: guardians of homeostasis in health and aging amid environmental challenges
Choi, J. & Augenlicht, L. H., Mar 2024, In: Experimental and Molecular Medicine. 56, 3, p. 495-500 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access81 Link opens in a new tab Scopus citations -
Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation
Verhagen, M. P., Joosten, R., Schmitt, M., Välimäki, N., Sacchetti, A., Rajamäki, K., Choi, J., Procopio, P., Silva, S., van der Steen, B., van den Bosch, T. P. P., Seinstra, D., de Vries, A. C., Doukas, M., Augenlicht, L. H., Aaltonen, L. A. & Fodde, R., Jul 2024, In: Nature Genetics. 56, 7, p. 1456-1467 12 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Link opens in a new tab Scopus citations