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Dive into the research topics where Julie Secombe is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Non-canonical mechanisms of gene regulation by the histone demethylase KDM5
Secombe, J. (PI)
National Institute of General Medical Sciences
9/22/23 → 8/31/26
Project: Research project
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MOLECULAR MECHANISMS UNDERLYING INTELLECTUAL DISABILITY CAUSED BY MUTATIONS IN THE CHROMATIN MODIFIER KDM5C
Secombe, J. (PI)
Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Child Health and Human Development
4/1/21 → 5/31/26
Project: Research project
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Activation of Endogenous Transposable Elements by Myc During Aging
Secombe, J. (PI) & Neretti, N. (CoPI)
9/1/17 → 4/30/18
Project: Research project
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Activation of Endogenous Transposable Elements by Myc During Aging
Secombe, J. (CoPI) & Secombe, J. (CoPI)
9/30/16 → 4/30/22
Project: Research project
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Local chromatin context informs transcriptional outcomes for the histone demethylase KDM5
Yheskel, M., Castiglione, M. A. & Secombe, J., Dec 2025, In: Epigenetics and Chromatin. 18, 1, 78.Research output: Contribution to journal › Article › peer-review
Open Access -
KDM5-mediated transcriptional activation of ribosomal protein genes alters translation efficiency to regulate mitochondrial metabolism in neurons
Yheskel, M., Hatch, H. A. M., Pedrosa, E., Terry, B. K., Siebels, A. A., Zheng, X. Y., Blok, L. E. R., Fencková, M., Sidoli, S., Schenck, A., Zheng, D., Lachman, H. M. & Secombe, J., Jun 24 2024, In: Nucleic acids research. 52, 11, p. 6201-6219 19 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
DVT: a high-throughput analysis pipeline for locomotion and social behavior in adult Drosophila melanogaster
Mi, K., Li, Y., Yang, Y., Secombe, J. & Liu, X., Dec 2023, In: Cell and Bioscience. 13, 1, 187.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Expression of retrotransposons contributes to aging in Drosophila
Schneider, B. K., Sun, S., Lee, M., Li, W., Skvir, N., Neretti, N., Vijg, J. & Secombe, J., Jun 2023, In: Genetics. 224, 2, iyad073.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
KDM5-mediated activation of genes required for mitochondrial biology is necessary for viability in Drosophila
Rogers, M. F., Marshall, O. J. & Secombe, J., Nov 2023, In: Development (Cambridge). 150, 21, dev202024.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations