Projects per year
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Collaborations and top research areas from the last five years
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A New Mode of Inhibition to Target Protein-Protein Interactions by Ligand-Transferred Oxidation
Maianti, J. P. (PI)
National Institute of General Medical Sciences
9/1/25 → 8/31/26
Project: Research project
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Chemical Synthesis Shared Resource
Schramm, V. V. L. (PI) & Maianti, J. P. (PI)
7/1/23 → 6/30/26
Project: Research project
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Cancer Center Support Grant
Almo, S. C. (CoPI), Hogue-Angeletti, R. (CoPI), Augenlicht, L. H. (CoPI), Condeelis, J. S. (CoPI), Desai, K. (CoPI), Edelmann, W. (CoPI), Goldman, I. D. (CoPI), Greally, J. M. (CoPI), Herbst, L. H. (CoPI), Keller, S. M. (CoPI), Kim, M. Y. (CoPI), Mahmood, R. (CoPI), Montagna, C. (CoPI), Morrow, B. E. (CoPI), Pollard, J. W. (CoPI), Porcelli, S. A. (CoPI), Rohan, T. E. (CoPI), Scharff, M. D. (CoPI), Seither, R. (CoPI), Skoultchi, A. I. (CoPI), Sparano, J. A. (CoPI), Stanley, P. M. (CoPI), Chu, E. E. (PI), Bresnick, A. R. (CoPI), Skoultchi, A. I. (CoPI), Adedimeji, A. A. (CoPI), Beck, A. A. P. (CoPI), Blanchard, J. S. (CoPI), Halmos, B. B. (CoPI), Morrow, B. E. (CoPI), Diamond, B. B. (CoPI), Will, B. B. (CoPI), Rapkin, B. D. (CoPI), Chu, E. (CoPI), Montagna, C. C. (CoPI), Stein, D. T. (CoPI), Gaertner, D. D. J. (CoPI), Chu, E. E. (CoPI), Ho, G. Y. (CoPI), Goel, S. (CoPI), Hosgood, H. D. H. (CoPI), Strickler, H. H. D. (CoPI), Pollard, J. J. W. (CoPI), Condeelis, J. J. S. (CoPI), Dutcher, J. J. P. (CoPI), Greally, J. J. (CoPI), Backer, J. M. (CoPI), Sparano, J. J. A. (CoPI), Maianti, J. P. (CoPI), Aguirre-ghiso, J. J. A. (CoPI), Gritsman, K. K. (CoPI), Herbst, L. H. (CoPI), Augenlicht, L. H. (CoPI), Cannizzaro, L. A. (CoPI), Hackett, L. L. E. (CoPI), Scharff, M. M. D. (CoPI), Brenowitz, M. D. (CoPI), Kim, M. (CoPI), Ohri, N. N. (CoPI), Stanley, P. (CoPI), Gupta, R. R. K. (CoPI), Depinho, R. R. A. (CoPI), Kucherlapati, R. (CoPI), Schramm, V. L. (CoPI), Keller, S. M. (CoPI), Almo, S. C. (CoPI), Porcelli, S. S. A. (CoPI), Rohan, T. E. (CoPI), Steidl, U. U. G. (CoPI), Edelmann, W. (CoPI), Xue, X. X. N. (CoPI), Alderman, M. H. (CoPI), Atkinson, P. H. (CoPI), Bases, R. E. (CoPI), Birshstein, B. K. (CoPI), Bloom, B. R. (CoPI), Blumenfeld, O. O. (CoPI), Brenowitz, M. D. (CoPI), Brewer, F. C. (CoPI), Buhl, S. (CoPI), Chance, M. R. (CoPI), Chase, J. W. (CoPI), Childs, G. J. (CoPI), Depinho, R. (CoPI), Depinho, R. A. (CoPI), Duran-reynals, M. L. (CoPI), Dutcher, J. P. (CoPI), Eagle, H. (CoPI), Fant, J. (CoPI), Gaertner, D. J. (CoPI), Grills, G. (CoPI), Gupta, R. K. (CoPI), Horwitz, S. B. (CoPI), Horwitz, M. S. (CoPI), Hurwitz, J. (CoPI), Kadish, A. S. (CoPI), Klinger, H. P. (CoPI), Krauter, K. S. (CoPI), Kucherlapati, R. S. (CoPI), Levine, W. G. (CoPI), Lilly, F. (CoPI), Maio, J. J. (CoPI), Maitra, U. (CoPI), Makman, M. H. (CoPI), Marians, K. J. (CoPI), Nathenson, S. G. (CoPI), Orr, G. A. (CoPI), Peisach, J. (CoPI), Pickering, K. (CoPI), Rajan, T. V. (CoPI), Reid, L. M. (CoPI), Rubin, C. S. (CoPI), Russel, R. (CoPI), Satir, B. H. (CoPI), Schildkraut, C. L. (CoPI), Schulman, L. H. (CoPI), Serrano, L. J. (CoPI), Shapiro, L. (CoPI), Shin, S.-I. (CoPI), Wadler, S. H. (CoPI), Warner, J. R. (CoPI), West, M. (CoPI) & Wiernik, P. H. (CoPI)
6/1/85 → 6/30/26
Project: Research project
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Excess cysteine drives conjugate formation and impairs proliferation of NRF2-activated cancer cells
Brain, J. A., Vigil, A. L. B. G., Davidsen, K., Itokawa, A., Jurasin, A. C., Kerbyson, H. J., Kobiesa, M., Hart, M. L., Yoon, S. J., Bellotti, P., Maianti, J. P., DeNicola, G. M. & Sullivan, L. B., Apr 2026, In: Nature Metabolism. 8, 4, p. 840-854 15 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Distinct outcomes from targeted perturbations of the multi-subunit SCFSkp2 E3 ubiquitin ligase in blocking Trp53/Rb1-null prostate tumorigenesis
Xue, Y., Zhu, L., Karan, S., Locker, J. D., Branch, C., Zhang, J., Hoang, B., Maianti, J. P., Zhao, H. & Schwartz, E. L., Dec 2025, In: Communications Biology. 8, 1, 278.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Insights into the Interaction Landscape of the EVH1 Domain of Mena
LaComb, L., Ghosh, A., Bonanno, J. B., Nilson, D. J., Poppel, A. J., Dada, L., Cahill, S. M., Maianti, J. P., Kitamura, S., Cowburn, D. & Almo, S. C., Sep 3 2024, In: Biochemistry. 63, 17, p. 2183-2195 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Author Correction: Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules (Nature Chemistry, (2018), 10, 7, (704-714), 10.1038/s41557-018-0033-8)
Usanov, D. L., Chan, A. I., Maianti, J. P. & Liu, D. R., Nov 1 2019, In: Nature Chemistry. 11, 11, p. 1067 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme
Maianti, J. P., Tan, G. A., Vetere, A., Welsh, A. J., Wagner, B. K., Seeliger, M. A. & Liu, D. R., Jun 1 2019, In: Nature Chemical Biology. 15, 6, p. 565-574 10 p.Research output: Contribution to journal › Article › peer-review
44 Link opens in a new tab Scopus citations