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Dive into the research topics where Jonathan R. Lai is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Human antibodies as broad alphavirus immunotherapeutics
Lai, J. R. (PI)
National Institute of Allergy and Infectious Diseases
6/6/25 → 5/31/26
Project: Research project
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Project 3: Vaccine Design [mRNA] VEEV/CHIKV (alphaviruses)
Lai, J. R. (PI)
National Institute of Allergy and Infectious Diseases
8/12/24 → 7/31/27
Project: Research project
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Flavivirus and Alphavirus ReVAMPP (FLARE)
Diamond, M. M. S. (PI), Schmidt, A. A. G. (CoPI), Desilva, A. A. M. (CoPI), Goss, C. C. (CoPI), Streblow, D. D. N. (CoPI), Crowe, J. E. (CoPI), Lai, J. R. (CoPI), Kuhn, R. J. (CoPI) & Weaver, S. C. (CoPI)
8/12/24 → 7/31/27
Project: Research project
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Developing a new bispecific antibody mimicking rapid antigen-specific memory CD8+ T cell-mediated protection
Lauvau, G. (PI) & Lai, J. R. (CoPI)
National Institute of Allergy and Infectious Diseases
6/1/23 → 5/31/25
Project: Research project
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Structure-based design of broad flavivirus immunogens
Lai, J. R. (PI)
National Institute of Allergy and Infectious Diseases
9/24/21 → 8/31/22
Project: Research project
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A two-component cocktail of engineered DIII nanoparticles elicits broadly neutralizing antibody responses against dengue virus in mice
Mariano, M. C., Jung, H. S., Vergnolle, O., Haskell, K., Evanson, L. R., Quevedo, G., Frei, J. C., Tong, K., Thackray, L. B., Diamond, M. S. & Lai, J. R., Jun 20 2025, In: iScience. 28, 6, 112534.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Avidity and variable domain spacing strongly influence the therapeutic potency of bispecific antibodies against Crimean-Congo hemorrhagic fever virus
Wang, A., Monticelli, S. R., Wirchnianski, A. S., Abelson, D. M., Kuehne, A. I., Bakken, R. R., Middlecamp, M., Weingart, M., Vergnolle, O., Bornholdt, Z. A., Moyer, C. L., Berrigan, J. L., West, B. R., Fels, J. M., Zeitlin, L., Herbert, A. S., Chandran, K., Bikash, C. R. & Lai, J. R., May 2025, In: mBio. 16, 5Research output: Contribution to journal › Article › peer-review
Open Access -
Erratum: Correction for Ramos et al., "Broadly protective bispecific antibodies that simultaneously target influenza virus hemagglutinin and neuraminidase" (mBio (2024) 15 7 DOI: 10.1128/mbio.01085-24.)
Ramos, K. E., Okba, N. M. A., Tan, J., Bandawane, P., Meade, P., Loganathan, M., Francis, B., Shulenin, S., Holtsberg, F. W., Aman, M. J., McMahon, M., Krammer, F. & Lai, J. R., Apr 9 2025, In: mBio. 16, 4, p. e0027825Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
One-Pot Expression and Assembly of Resurfaced Zika Virus E Domain III Nanoparticle Immunogens in Mammalian Cells
Jung, H. S., Bikash, C. R., Tao, K. L. & Lai, J. R., Jun 17 2025, In: ACS Omega. 10, 23, p. 25068-25075 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The alphavirus determinants of intercellular long extension formation
Martin, C. K., Wan, J. J., Yin, P., Morrison, T. E., Messer, W. B., Rivera-Amill, V., Lai, J. R., Grau, N., Rey, F. A., Couderc, T., Lecuit, M. & Kielian, M., Feb 2025, In: mBio. 16, 2Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations