Projects per year
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Dive into the research topics where Edward L. Schwartz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Grants
- 16 Finished
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Vulnerability of SCLC based on bi-allelic genetic inactivation of RB1 and TP53
Zhao, H. (CoPI) & Schwartz, E. L. (PI)
4/12/19 → 3/31/22
Project: Research project
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Vulnerability of SCLC based on bi-allelic genetic inactivation of RB1 and TP53
Schwartz, E. L. (PI) & Zhao, H. (CoPI)
4/12/19 → 3/31/24
Project: Research project
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Dissecting Skp2 functions in pRb and p53 doubly deficient tumorigenesis
Schwartz, E. L. (PI)
6/3/16 → 5/31/21
Project: Research project
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Dissecting Skp2 functions in pRb and p53 doubly deficient tumorigenesis
Schwartz, E. L. (PI), Zhao, H. (CoPI) & Zhu, L. (CoPI)
6/3/16 → 5/31/21
Project: Research project
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Interactions of the angiopoietin and PD-ECGF pathways in tumor angiogenesis
Schwartz, E. L. (PI), Schwartz, E. L. (PI), Rose, S. A. (PI) & Rose, S. A. (PI)
7/9/12 → 5/31/18
Project: Research project
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Distinct outcomes from targeted perturbations of the multi-subunit SCFSkp2 E3 ubiquitin ligase in blocking Trp53/Rb1-null prostate tumorigenesis
Xue, Y., Zhu, L., Karan, S., Locker, J. D., Branch, C., Zhang, J., Hoang, B., Maianti, J. P., Zhao, H. & Schwartz, E. L., Dec 2025, In: Communications Biology. 8, 1, 278.Research output: Contribution to journal › Article › peer-review
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SKP2 knockout in Rb1/p53 deficient mouse models of osteosarcoma induces immune infiltration and drives a transcriptional program with a favorable prognosis
Ferrena, A., Wang, J., Zhang, R., Karadal-Ferrena, B., Al-Hardan, W., Singh, S., Borjihan, H., Schwartz, E. L., Zhao, H., Oktay, M. H., Yang, R., Geller, D. S., Hoang, B. H. & Zheng, D., Feb 10 2024, In: Molecular cancer therapeutics. 23, 2Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Targeted inhibition of SCFSKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma
Wang, J., Ferrena, A., Zhang, R., Singh, S., Viscarret, V., Al-Harden, W., Aldahamsheh, O., Borjihan, H., Singla, A., Yaguare, S., Tingling, J., Zi, X., Lo, Y., Gorlick, R., Schwartz, E. L., Zhao, H., Yang, R., Geller, D. S., Zheng, D. & Hoang, B. H., Mar 22 2024, In: Oncogene. 43, 13, p. 962-975 14 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Targeting the untargetable: RB1-deficient tumours are vulnerable to Skp2 ubiquitin ligase inhibition
Gupta, P., Zhao, H., Hoang, B. & Schwartz, E. L., Oct 5 2022, In: British Journal of Cancer. 127, 6, p. 969-975 7 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
The interaction of SKP2 with p27 enhances the progression and stemness of osteosarcoma
Wang, J., Aldahamsheh, O., Ferrena, A., Borjihan, H., Singla, A., Yaguare, S., Singh, S., Viscarret, V., Tingling, J., Zi, X., Lo, Y., Gorlick, R., Zheng, D., Schwartz, E. L., Zhao, H., Yang, R., Geller, D. S. & Hoang, B. H., Feb 18 2021, In: Annals of the New York Academy of Sciences. 1490, 1, p. 90-104 15 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations