No photo of Dongsheng Cai

View Scopus Profile

Dongsheng Cai, Ph.D., M.D.

Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
20002022

Research activity per year

Filter
Article

Search results

  • 2022

    Young cerebrospinal fluid contains key rejuvenating factors

    Zhang, D. & Cai, D., Oct 1 2022, In: Life Metabolism. 1, 2, p. 103-104 2 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
  • 2021

    Exosomes/microvesicles target SARS-CoV-2 via innate and RNA-induced immunity with PIWI-piRNA system

    Ikhlas, S., Usman, A., Kim, D. & Cai, D., Mar 2021, In: Life Science Alliance. 5, 3, e202101240.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • GnRH pulse frequency and irregularity play a role in male aging

    Wang, Z., Wu, W., Kim, M. S. & Cai, D., Oct 2021, In: Nature Aging. 1, 10, p. 904-918 15 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations
  • 2020

    Aging-induced aberrant RAGE/PPARα axis promotes hepatic steatosis via dysfunctional mitochondrial β oxidation

    Wan, J., Wu, X., Chen, H., Xia, X., Song, X., Chen, S., Lu, X., Jin, J., Su, Q., Cai, D., Liu, B. & Li, B., Oct 1 2020, In: Aging cell. 19, 10, e13238.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    28 Scopus citations

  • Brain is an endocrine organ through secretion and nuclear transfer of parathymosin

    Yu, B., Tang, Y. & Cai, D., Oct 21 2020, In: Life Science Alliance. 3, 12, e202000917.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Control of lifespan and survival by Drosophila NF-KB signaling through neuroendocrine cells and neuroblasts

    Khor, S. & Cai, D., Dec 31 2020, In: Aging. 12, 24, p. 24604-24622 19 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3 Scopus citations

  • Hypothalamic extended synaptotagmin-3 contributes to the development of dietary obesity and related metabolic disorders

    Zhang, Y., Guan, Y., Pan, S., Yan, L., Wang, P., Chen, Z., Shen, Q., Zhao, F., Zhang, X., Li, J., Li, J., Cai, D. & Zhang, G., Aug 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 33, p. 20149-20158 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Innate and Adaptive Immunity of Murine Neural Stem Cell-Derived piRNA Exosomes/Microvesicles against Pseudotyped SARS-CoV-2 and HIV-Based Lentivirus

    Yu, B., Ikhlas, S., Ruan, C., Zhong, X. & Cai, D., Dec 18 2020, In: iScience. 23, 12, 101806.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    14 Scopus citations

  • Multifaceted secretion of htNSC-derived hypothalamic islets induces survival and antidiabetic effect via peripheral implantation in mice

    Tang, Y., Zuniga, J. P. H., Han, C., Yu, B. & Cai, D., Feb 2020, In: eLife. 9, e52580.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline

    Xiao, Y. Z., Yang, M., Xiao, Y., Guo, Q., Huang, Y., Li, C. J., Cai, D. & Luo, X. H., Mar 3 2020, In: Cell metabolism. 31, 3, p. 534-548.e5

    Research output: Contribution to journal › Article › peer-review

    Open Access
    75 Scopus citations

  • Regulation of muscle and metabolic physiology by hypothalamic erythropoietin independently of its peripheral action

    Wang, Z., Khor, S. & Cai, D., Feb 2020, In: Molecular Metabolism. 32, p. 56-68 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1

    Shen, Q., Chen, Z., Zhao, F., Pan, S., Zhang, T., Cheng, X., Zhang, L., Zhang, S., Qi, J., Li, J., Cai, D. & Zhang, G., Jul 1 2020, In: Nature Neuroscience. 23, 7, p. 832-841 10 p.

    Research output: Contribution to journal › Article › peer-review

    21 Scopus citations
  • 2019

    Age-dependent decline of hypothalamic HIF2 in response to insulin and its contribution to advanced age-associated metabolic disorders in mice

    Wang, Z., Khor, S. & Cai, D., Mar 29 2019, In: Journal of Biological Chemistry. 294, 13, p. 4946-4955 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations
  • 2018

    MiR199a-5p inhibits hepatic insulin sensitivity via suppression of ATG14-mediated autophagy article

    Li, B., Wu, X., Chen, H., Zhuang, C., Zhang, Z., Yao, S., Cai, D., Ning, G. & Su, Q., Mar 1 2018, In: Cell Death and Disease. 9, 3, 405.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    19 Scopus citations
  • 2017

    Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight

    Zhang, Y., Reichel, J. M., Han, C., Zuniga-Hertz, J. P. & Cai, D., May 2 2017, In: Cell metabolism. 25, 5, p. 1091-1102.e4

    Research output: Contribution to journal › Article › peer-review

    Open Access
    114 Scopus citations

  • Hypothalamic and inflammatory basis of hypertension

    Khor, S. & Cai, D., 2017, In: Clinical Science. 131, 3, p. 211-223 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

    Zhang, Y., Kim, M. S., Jia, B., Yan, J., Zuniga-Hertz, J. P., Han, C. & Cai, D., Aug 3 2017, In: Nature. 548, 7665, p. 52-57 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    387 Scopus citations

  • Neural programmatic role of leptin, TNFα, melanocortin, and glutamate in blood pressure regulation vs obesity-related hypertension in male C57BL/6 mice

    Yu, B. & Cai, D., Jun 1 2017, In: Endocrinology. 158, 6, p. 1766-1775 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • Obesity-associated extracellular mtDNA activates central TGFβ pathway to cause blood pressure increase

    Alé, A., Zhang, Y., Han, C. & Cai, D., 2017, In: American Journal of Physiology - Endocrinology and Metabolism. 312, 3, p. E161-E174

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations
  • 2016

    Berberine prevents progression from hepatic steatosis to steatohepatitis and fibrosis by reducing endoplasmic reticulum stress

    Zhang, Z., Li, B., Meng, X., Yao, S., Jin, L., Yang, J., Wang, J., Zhang, H., Zhang, Z., Cai, D., Zhang, Y. & Ning, G., Feb 9 2016, In: Scientific reports. 6, 20848.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    80 Scopus citations

  • Canonical transient receptor potential 3 channels activate NF-κB to mediate allergic airway disease via PKC-α/IκB-α and calcineurin/IκB-β pathways

    Song, T., Zheng, Y. M., Vincent, P. A., Cai, D., Rosenberg, P. & Wang, Y. X., Jan 1 2016, In: FASEB Journal. 30, 1, p. 214-229 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    19 Scopus citations

  • Central leptin and tumor necrosis factor-α (TNFα) in diurnal control of blood pressure and hypertension

    Han, C., Wu, W., Ale, A., Kim, M. S. & Cai, D., Jul 15 2016, In: Journal of Biological Chemistry. 291, 29, p. 15131-15142 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations
  • 2015

    Metabolic learning and memory formation by the brain influence systemic metabolic homeostasis

    Zhang, Y., Liu, G., Yan, J., Zhang, Y., Li, B. & Cai, D., Apr 13 2015, In: Nature communications. 6, 6704.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Rapid linkage of innate immunological signals to adaptive immunity by the brain-fat axis

    Kim, M. S., Yan, J., Wu, W., Zhang, G., Zhang, Y. & Cai, D., May 28 2015, In: Nature Immunology. 16, 5, p. 525-533 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations
  • 2014

    Aberrant mir199a-5p/caveolin1/PPARα axis in hepatic steatosis

    Li, B., Zhang, Z., Zhang, H., Quan, K., Lu, Y., Cai, D. & Ning, G., Oct 13 2014, In: Journal of Molecular Endocrinology. 53, 3, p. 393-403 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    43 Scopus citations

  • Control of obesity and glucose intolerance via building neural stem cells in the hypothalamus

    Li, J., Tang, Y., Purkayastha, S., Yan, J. & Cai, D., Jun 2014, In: Molecular Metabolism. 3, 3, p. 313-324 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • Obesity-and aging-induced excess of central transforming growth factor-β 2 potentiates diabetic development via an RNA stress response

    Yan, J., Zhang, H., Yin, Y., Li, J., Tang, Y., Purkayastha, S., Li, L. & Cai, D., Sep 1 2014, In: Nature Medicine. 20, 9, p. 1001-1008 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    109 Scopus citations

  • Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα

    Lu, Y., Liu, X., Jiao, Y., Xiong, X., Wang, E., Wang, X., Zhang, Z., Zhang, H., Pan, L., Guan, Y., Cai, D., Ning, G. & Li, X., Aug 1 2014, In: Journal of Clinical Investigation. 124, 8, p. 3501-3513 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    112 Scopus citations
  • 2013

    Counterbalance between BAG and URX neurons via guanylate cyclases controls lifespan homeostasis in C. elegans

    Liu, T. & Cai, D., May 29 2013, In: EMBO Journal. 32, 11, p. 1529-1542 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    20 Scopus citations

  • Disruption of neurogenesis by hypothalamic inflammation in obesity or aging

    Purkayastha, S. & Cai, D., Dec 2013, In: Reviews in Endocrine and Metabolic Disorders. 14, 4, p. 351-356 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

    Zhang, G., Li, J., Purkayastha, S., Tang, Y., Zhang, H., Yin, Y., Li, B., Liu, G. & Cai, D., 2013, In: Nature. 497, 7448, p. 211-216 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    661 Scopus citations

  • Sustained NF-κB Activation and Inhibition in β-Cells Have Minimal Effects on Function and Islet Transplant Outcomes

    King, A. J. F., Guo, Y., Cai, D., Hollister-Lock, J., Morris, B., Salvatori, A., Corbett, J. A., Bonner-Weir, S., Shoelson, S. E. & Weir, G. C., Oct 18 2013, In: PloS one. 8, 10, e77452.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Treatment of Obesity and Diabetes Using Oxytocin or Analogs in Patients and Mouse Models

    Zhang, H., Wu, C., Chen, Q., Chen, X., Xu, Z., Wu, J. & Cai, D., May 20 2013, In: PloS one. 8, 5, e61477.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    196 Scopus citations
  • 2012

    Guidelines for the use and interpretation of assays for monitoring autophagy

    Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J. U., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J., & 1,249 othersAleo, M. F. R., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. H. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W. L., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H. I., Cho, D. H., Choi, A. M. K., Choi, D. S., Choi, K. S. O., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M. A., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., de Groot, J. F., de Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z. H., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Eng, K. E. R., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M. A., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A. N., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E. L., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M. I., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J. I., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H. W., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B. E., Kang, K. I. L., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R. Y., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H. U., Kim, J. C. H., Kim, J. K., Kim, P. K., Kim, S. W. H., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H. O., Koike, M., Komatsu, M., Kominami, E., Kong, H. J. E., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Krämer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J. E., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M. I., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H. Y., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. L., Li, L., Li, S., Li, W., Li, X. J., Li, Y. B., Li, Y. P., Liang, C., Liang, Q., Liao, Y. F., Liberski, P. P., Lieberman, A., Lim, H. J., Lim, K. L., Lim, K., Lin, C. F., Lin, F. C., Lin, J., Lin, J. D., Lin, K., Lin, W. W., Lin, W. C., Lin, Y. L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M. P., Liton, P. B., Liu, B., Liu, C. F., Liu, K., Liu, L., Liu, Q. A., Liu, W., Liu, Y. C., Liu, Y., Lockshin, R. A., Lok, C. N., Lonial, S., Loos, B., Lopez-Berestein, G., López-Otín, C., Lossi, L., Lotze, M. T., Lőw, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N. W., Lund, A. H., Lynch-Day, M. A., Ma, Y., Macian, F., MacKeigan, J. P., Macleod, K. F., Madeo, F., Maiuri, L., Maiuri, M. C. H., Malagoli, D., Malicdan, M. C. H. V., Malorni, W., Man, N., Mandelkow, E. M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y. L., Marchbank, K., Marchetti, P., Marciniak, S. J., Marcondes, M., Mardi, M., Marfe, G., Mariño, G., Markaki, M., Marten, M. R., Martin, S. J., Martinand-Mari, C., Martinet, W., Martinez-Vicente, M., Masini, M., Matarrese, P., Matsuo, S., Matteoni, R., Mayer, A., Mazure, N. M., McConkey, D. J., McConnell, M. J., McDermott, C., McDonald, C., McInerney, G. M., McKenna, S. L., McLaughlin, B. A., McLean, P. J., McMaster, C. R., McQuibban, G. A., Meijer, A. J., Meisler, M. H., Meléndez, A., Melia, T. J., Melino, G., Mena, M. A., Menendez, J. A., Menna-Barreto, R. F. S., Menon, M. B., Menzies, F. M., Mercer, C. A., Merighi, A., Merry, D. E., Meschini, S., Meyer, C. G., Meyer, T. F., Miao, C. Y., Miao, J. Y., Michels, P. A. M., Michiels, C., Mijaljica, D., Milojkovic, A., Minucci, S., Miracco, C., Miranti, C. K., Mitroulis, I., Miyazawa, K., Mizushima, N., Mograbi, B., Mohseni, S., Molero, X., Mollereau, B., Mollinedo, F., Momoi, T., Monastyrska, I., Monick, M. M., Monteiro, M. J., Moore, M. N., Mora, R., Moreau, K., Moreira, P. I., Moriyasu, Y., Moscat, J., Mostowy, S., Mottram, J. C., Motyl, T., Moussa, C. E. H., Müller, S., Muller, S., Münger, K., Münz, C., Murphy, L. O., Murphy, M. E., Musarò, A., Mysorekar, I., Nagata, E., Nagata, K., Nahimana, A., Nair, U., Nakagawa, T., Nakahira, K., Nakano, H., Nakatogawa, H., Nanjundan, M., Naqvi, N. I., Narendra, D. P., Narita, M., Navarro, M., Nawrocki, S. T., Nazarko, T. Y., Nemchenko, A., Netea, M. G., Neufeld, T. P., Ney, P. A., Nezis, I. P., Nguyen, H. P. H., Nie, D., Nishino, I., Nislow, C., Nixon, R. A., Noda, T., Noegel, A. A., Nogalska, A., Noguchi, S., Notterpek, L., Novak, I., Nozaki, T., Nukina, N., Nürnberger, T., Nyfeler, B., Obara, K., Oberley, T. D., Oddo, S., Ogawa, M., Ohashi, T., Okamoto, K., Oleinick, N. L., Oliver, F. J., Olsen, L. J., Olsson, S., Opota, O., Osborne, T. F., Ostrander, G. K., Otsu, K., Ou, J. H. J., Ouimet, M., Overholtzer, M., Ozpolat, B., Paganetti, P., Pagnini, U., Pallet, N., Palmer, G. E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U. B. H., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O. K., Parys, J. B., Parzych, K. R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J. M., Peng, J., Perlmutter, D. H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G. J., Petersen, M., Petrovski, G., Phang, J. M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L. C., Pöggeler, S., Poirot, M., Poletti, A., Poüs, C., Pozuelo-Rubio, M., Prætorius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S. B., Qin, L., Qin, Z. H., Quaggin, S. E., Raben, N., Rabinowich, H., Rabkin, S. W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V. A., Rathmell, J. C., Ravikumar, B., Ray, S. K., Reed, B. H., Reed, J. C., Reggiori, F., Régnier-Vigouroux, A., Reichert, A. S., Reiners, J. J., Reiter, R. J., Ren, J., Revuelta, J. L., Rhodes, C. J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M. C., Rocchi, S., Rodemann, H. P., Rodríguez de Córdoba, S., Rohrer, B., Roninson, I. B., Rosen, K., Rost-Roszkowska, M. M., Rouis, M., Rouschop, K. M. A., Rovetta, F., Rubin, B. P., Rubinsztein, D. C., Ruckdeschel, K., Rucker, E. B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T. E. R., Ryan, K. M., Ryter, S. W., Sabatini, D. M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G. H. O., Salomoni, P., Salvaterra, P. M., Salvesen, G., Salvioli, R., Sanchez, A. M. J., Sánchez-Alcázar, J. A., Sánchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A. H. V., Scharl, M., Schätzl, H. M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M. E., Schneider-Stock, R., Schoenlein, P. V., Schorderet, D. F., Schüller, C., Schwartz, G. K., Scorrano, L., Sealy, L., Seglen, P. O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J. B. O., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J. J., Shanmugam, M., Shapiro, I. M., Shaulian, E., Shaw, R. J., Shelhamer, J. H., Shen, H. M., Shen, W. C., Sheng, Z. H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J. J., Shih, C. M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O. S., Shore, G. C., Sibirny, A. A., Sidhu, S. B., Sikorska, B., Silva-Zacarin, E. C. M., Simmons, A., Simon, A. K. A., Simon, H. U., Simone, C., Simonsen, A., Sinclair, D. A., Singh, R., Sinha, D., Sinicrope, F. A., Sirko, A., Siu, P. M., Sivridis, E., Skop, V., Skulachev, V. P., Slack, R. S., Smaili, S. S., Smith, D. R., Soengas, M. S., Soldati, T., Song, X., Sood, A. K., Soong, T. W. A., Sotgia, F., Spector, S. A., Spies, C. D., Springer, W., Srinivasula, S. M., Stefanis, L., Steffan, J. S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S. T., Sternberg, C., Stork, B., Strålfors, P., Subauste, C. S., Sui, X., Sulzer, D., Sun, J., Sun, S. Y., Sun, Z. J., Sung, J. J. Y., Suzuki, K., Suzuki, T., Swanson, M. S., Swanton, C., Sweeney, S. T., Sy, L. K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Takács-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N. J., Tan, K. S. W., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B. A., Tavernarakis, N., Taylor, G. S., Taylor, G. A., Taylor, J. P., Terada, L. S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C. B., Thorburn, A., Thumm, M., Tian, F. F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A. M., Tomino, Y., Tönges, L., Tooze, S. A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L. H., Tsai, T. F., Tschan, M. P., Tsubata, T., Tsung, A., Turk, B., Turner, L. S., Tyagi, S. C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V. K., Vaccaro, M. I., Valente, E. M. A., Van den Berghe, G., van der Klei, I. J., van Doorn, W., van Dyk, L. F., van Egmond, M., van Grunsven, L. A., Vandenabeele, P., Vandenberghe, W. P., Vanhorebeek, I., Vaquero, E. C., Velasco, G., Vellai, T., Vicencio, J. M. I., Vierstra, R. D., Vila, M., Vindis, C., Viola, G., Viscomi, M. T. E., Voitsekhovskaja, O. V., von Haefen, C., Votruba, M., Wada, K., Wade-Martins, R., Walker, C. L., Walsh, C. M., Walter, J., Wan, X. B., Wang, A., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H. G., Wang, H. D., Wang, J., Wang, K., Wang, M., Wang, R. C., Wang, X., Wang, X., Wang, Y. J., Wang, Y., Wang, Z., Wang, Z. C. H., Wang, Z., Wansink, D. G., Ward, D. M., Watada, H., Waters, S. L., Webster, P., Wei, L., Weihl, C. C., Weiss, W. A., Welford, S. M., Wen, L. P., Whitehouse, C. A., Whitton, J. L., Whitworth, A. J., Wileman, T., Wiley, J. W., Wilkinson, S., Willbold, D., Williams, R. L., Williamson, P. R., Wouters, B. G., Wu, C., Wu, D. C., Wu, W. K. K., Wyttenbach, A., Xavier, R. J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D. Z., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D. S., Yang, E., Yang, J. M., Yang, S. Y. U., Yang, W., Yang, W. Y. U., Yang, Z., Yao, M. C., Yao, T. P., Yeganeh, B., Yen, W. L., Yin, J. J., Yin, X. M., Yoo, O. J., Yoon, G., Yoon, S. Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H. J. I., Youle, R. J., Younes, A., Yu, L., Yu, L., Yu, S. W., Yu, W. H. A., Yuan, Z. M., Yue, Z., Yun, C. H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., Zacks, D., Zacksenhaus, E., Zaffaroni, N., Zakeri, Z., Zeh, H. J., Zeitlin, S. O., Zhang, H., Zhang, H. L., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X. D. O., Zhao, M., Zhao, Y. F., Zhao, Y., Zhao, Z. J., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, C. Z., Zhu, C., Zhu, W. G., Zhu, X. F., Zhu, X., Zhu, Y., Zoladek, T., Zong, W. X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 1 2012, In: Autophagy. 8, 4, p. 445-544 100 p.

    Research output: Contribution to journal › Article › peer-review

    2885 Scopus citations

  • IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

    Li, J., Tang, Y. & Cai, D., Oct 2012, In: Nature Cell Biology. 14, 10, p. 999-1012 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    292 Scopus citations

  • Inflammatory cause of metabolic syndrome via brain stress and NF-κB

    Cai, D. & Liu, T., Feb 2012, In: Aging. 4, 2, p. 98-115 18 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    155 Scopus citations

  • Shp2 controls female body weight and energy balance by integrating leptin and estrogen signals

    He, Z., Zhang, S. S., Meng, Q., Li, S., Zhu, H. H., Raquil, M. A., Alderson, N., Zhang, H., Wu, J., Rui, L., Cai, D. & Feng, G. S., May 2012, In: Molecular and cellular biology. 32, 10, p. 1867-1878 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    52 Scopus citations
  • 2011

    Circadian intervention of obesity development via resting-stage feeding manipulation or oxytocin treatment

    Zhang, G. & Cai, D., Nov 2011, In: American Journal of Physiology - Endocrinology and Metabolism. 301, 5, p. E1004-E1012

    Research output: Contribution to journal › Article › peer-review

    Open Access
    139 Scopus citations

  • Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IκB kinase β(IKKβ)/NF-κB pathway

    Meng, Q. & Cai, D., Sep 16 2011, In: Journal of Biological Chemistry. 286, 37, p. 32324-32332 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    199 Scopus citations

  • Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation

    Zhang, H., Zhang, G., Gonzalez, F. J., Park, S. M. & Cai, D., Jul 2011, In: PLoS biology. 9, 7, e1001112.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    82 Scopus citations

  • Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress

    Purkayastha, S., Zhang, H., Zhang, G., Ahmed, Z., Wang, Y. & Cai, D., Feb 15 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 7, p. 2939-2944 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    142 Scopus citations

  • Neuropeptide Exocytosis Involving Synaptotagmin-4 and Oxytocin in Hypothalamic Programming of Body Weight and Energy Balance

    Zhang, G., Bai, H., Zhang, H., Dean, C., Wu, Q., Li, J., Guariglia, S., Meng, Q. & Cai, D., Feb 10 2011, In: Neuron. 69, 3, p. 523-535 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    169 Scopus citations

  • Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-Î 2 and NF-ΰB

    Purkayastha, S., Zhang, G. & Cai, D., Jul 2011, In: Nature Medicine. 17, 7, p. 883-887 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    190 Scopus citations
  • 2008

    Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

    Zhang, X., Zhang, G., Zhang, H., Karin, M., Bai, H. & Cai, D., Oct 3 2008, In: Cell. 135, 1, p. 61-73 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1125 Scopus citations

  • Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes

    Goldfine, A. B., Silver, R., Aldhahi, W., Cai, D., Tatro, E., Lee, J. & Shoelson, S. E., 2008, In: Clinical and Translational Science. 1, 1, p. 36-43 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    251 Scopus citations
  • 2005

    Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB

    Cai, D., Yuan, M., Frantz, D. F., Melendez, P. A., Hansen, L., Lee, J. & Shoelson, S. E., Feb 2005, In: Nature Medicine. 11, 2, p. 183-190 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1889 Scopus citations

  • Regulation of IκB kinase and NF-κB in contracting adult rat skeletal muscle

    Ho, R. C., Hirshman, M. F., Li, Y., Cai, D., Farmer, J. R., Aschenbach, W. G., Witczak, C. A., Shoelson, S. E. & Goodyear, L. J., Oct 2005, In: American Journal of Physiology - Cell Physiology. 289, 4 58-4, p. C794-C801

    Research output: Contribution to journal › Article › peer-review

    99 Scopus citations
  • 2004

    IKKβ/NF-κB activation causes severe muscle wasting in mice

    Cai, D., Frantz, J. D., Tawa, N. E., Melendez, P. A., Oh, B. C., Lidov, H. G. W., Hasselgren, P. O., Frontera, W. R., Lee, J., Glass, D. J. & Shoelson, S. E., Oct 15 2004, In: Cell. 119, 2, p. 285-298 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1122 Scopus citations
  • 2003

    Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5

    Cai, D., Dhe-Paganon, S., Melendez, P. A., Lee, J. & Shoelson, S. E., Jul 11 2003, In: Journal of Biological Chemistry. 278, 28, p. 25323-25330 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    161 Scopus citations
  • 2001

    [Effects of hypothyroidism on Goalpha gene expression in hippocampus and dentate gyrus during early development of rat brain].

    Cai, D. S., Chen, Y., Chen, G. & Luo, M., Feb 2001, In: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 17, 1, p. 21-24 4 p.

    Research output: Contribution to journal › Article › peer-review