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Dive into the research topics where Derek M. Huffman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Connecting surgical stress to sex-dependent vulnerabilities in aging and aging hallmarks
Huffman, D. M. (PI) & Fooksman, D. D. R. (CoPI)
9/1/25 → 8/31/27
Project: Research project
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Development of a Growth Hormone Receptor antagonist for the delay or prevention of ADRD
Brody, R. R. S. (PI), Huffman, D. M. (CoPI), Kopchick, J. J. J. (CoPI) & Milman, S. (CoPI)
2/15/24 → 1/31/26
Project: Research project
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Einstein's Nathan Shock Center of Excellence in Basic Biology of Aging
Milman, S. S. (PI) & Huffman, D. M. (PI)
6/1/23 → 5/31/25
Project: Research project
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Deciphering the enigmatic role of IGF-1 signaling in cognitive decline and Alzheimer's disease
Huffman, D. M. (CoPI)
9/15/20 → 8/31/21
Project: Research project
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Deciphering the enigmatic role of IGF-1 signaling in cognitive decline and Alzheimer's disease
Huffman, D. M. (PI) & Gandy, S. (CoPI)
9/15/20 → 8/31/21
Project: Research project
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An engineered insulin analog with dual insulin and IGF-1 receptor agonism and distinct signaling
Selicharová, I., Kirk, N. S., Kertisová, A., Lubos, M., Mitrová, K., Ticháčková, T., Žáková, L., Chrudinová, M., Březinová, J., Harant, K., Voldřich, J., Hájek, M., Huffman, D. M. & Jiráček, J., 2026, In: Science Advances. 12, 20, eaeb7558.Research output: Contribution to journal › Article › peer-review
Open Access -
Plasma-based strategies for systemic rejuvenation: critical perspectives on clinical translation
Gulej, R., Patai, R., Ungvari, A., Tordai, A., Huffman, D. M., Tarantini, S., Yabluchanskiy, A., Ungvari, Z. & Csiszar, A., Jun 2026, In: GeroScience. 48, 3, p. 4571-4584 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity
Stransky, S., Graff, S., Mao, K., Huffman, D. M., Milman, S., Barzilai, N. & Sidoli, S., Jan 2026, In: Aging cell. 25, 1, e70346.Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Scopus citations -
Reduced IGF-1 signaling fails to limit Alzheimer’s disease progression in a novel rat model of IGF-1R haploinsufficiency
Narayan, S., Mao, K., Williams-Medina, A. R., Richmann, T., Gal, M., Engel, M., Zhang, Y., Graff, S., Sidoli, S., Barzilai, N. & Huffman, D. M., Dec 2026, In: Scientific reports. 16, 1, 1856.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
The glycine N-methyltransferase amino-terminus regulates folate-dependent feedback inhibition and S-adenosylmethionine homeostasis
Kraz, I., Mak, O. W., Hegde, S., Lorton, B. M., Hector, H., Broussalian, M. K., Graff, S., Aguilan, J., Bonanno, J., Eskandari, R., Groom, D., Sidoli, S., Almo, S., Brenowitz, M., Gavathiotis, E., Huffman, D. M. & Shechter, D., Oct 2026, In: Journal of Biological Chemistry. 302, 10, 113468.Research output: Contribution to journal › Article › peer-review
Open Access