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Dive into the research topics where Derek M. Huffman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Connecting surgical stress to sex-dependent vulnerabilities in aging and aging hallmarks
Huffman, D. M. (PI) & Fooksman, D. D. R. (CoPI)
9/1/25 → 8/31/27
Project: Research project
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Development of a Growth Hormone Receptor antagonist for the delay or prevention of ADRD
Brody, R. R. S. (PI), Huffman, D. M. (CoPI), Kopchick, J. J. J. (CoPI) & Milman, S. (CoPI)
2/15/24 → 1/31/26
Project: Research project
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Einstein's Nathan Shock Center of Excellence in Basic Biology of Aging
Milman, S. S. (PI) & Huffman, D. M. (PI)
6/1/23 → 5/31/25
Project: Research project
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Deciphering the enigmatic role of IGF-1 signaling in cognitive decline and Alzheimer's disease
Huffman, D. M. (CoPI)
9/15/20 → 8/31/21
Project: Research project
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Deciphering the enigmatic role of IGF-1 signaling in cognitive decline and Alzheimer's disease
Huffman, D. M. (PI) & Gandy, S. (CoPI)
9/15/20 → 8/31/21
Project: Research project
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Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity
Stransky, S., Graff, S., Mao, K., Huffman, D. M., Milman, S., Barzilai, N. & Sidoli, S., Jan 2026, In: Aging cell. 25, 1, e70346.Research output: Contribution to journal › Article › peer-review
Open Access -
Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape
Dubey, A., Yamashita, E., Stangeland, B., Abbas, I., Fooksman, D., Harris, R. A., Palmer, G. M., Koba, W. R., Zhang, J., Himes, B. T., Lu, O. R., Ho, W. S., Kuiper, R. V., Huffman, D., Wu, Z., Uchida, Y., Ishii, M., Welch, R. L., Fiedler, A. F. & Reynolds, D. M. & 8 others, , Nov 2025, In: Nature Neuroscience. 28, 11, p. 2231-2246 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Correction to: Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape (Nature Neuroscience, (2025), 28, 11, (2231-2246), 10.1038/s41593-025-02064-4)
Dubey, A., Yamashita, E., Stangeland, B., Abbas, I., Fooksman, D., Harris, R. A., Palmer, G. M., Koba, W. R., Zhang, J., Himes, B. T., Lu, O. R., Ho, W. S., Kuiper, R. V., Huffman, D., Wu, Z., Uchida, Y., Ishii, M., Welch, R. L., Fiedler, A. F. & Reynolds, D. M. & 8 others, , Dec 2025, In: Nature Neuroscience. 28, 12, p. 2645 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Impacts of systemic milieu on cerebrovascular and brain aging: insights from heterochronic parabiosis, blood exchange, and plasma transfer experiments
Gulej, R., Patai, R., Ungvari, A., Kallai, A., Tarantini, S., Yabluchanskiy, A., Huffman, D. M., Conboy, M. J., Conboy, I. M., Kivimäki, M., Csiszar, A. & Ungvari, Z., Oct 2025, In: GeroScience. 47, 5, p. 6207-6376 170 p.Research output: Contribution to journal › Review article › peer-review
Open Access8 Scopus citations -
Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice
Engel, M. G., Narayan, S., Cui, M. H., Branch, C. A., Zhang, X., Gandy, S. E., Ehrlich, M. & Huffman, D. M., Jan 2025, In: Journal of Alzheimer's Disease. 103, 1, p. 113-126 14 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations