Projects per year
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Collaborations and top research areas from the last five years
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SPORE in Prostate Cancer
Chen, Y. Y. (PI), Allison, J. P. (CoPI), Gopalan, A. A. (CoPI), Carver, B. S. (CoPI), Solit, D. D. B. (CoPI), Gerald, W. L. (CoPI), Gregor, P. D. (CoPI), Heller, G. (CoPI), Scher, H. H. I. (CoPI), Heller, G. G. (CoPI), Koutcher, J. A. (CoPI), Lilja, H. (CoPI), Morris, M. (CoPI), Eastham, J. J. A. (CoPI), Pandolfi, P. P. P. P. (CoPI), Reuter, V. E. (CoPI), Reuter, V. (CoPI), Rosen, N. (CoPI), Sawyers, C. L. (CoPI), Scardino, P. T. (CoPI), Socci, N. D. (CoPI), Taylor, B. S. (CoPI), Di Cristofano, A. (CoPI), Kattan, M. W. (CoPI) & Rueter, V. E. (CoPI)
9/14/01 → 8/31/26
Project: Research project
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SPORE in Thyroid Cancer
Fagin, J. A. (PI), Berger, M. (CoPI), Chan, T.A.-T. (CoPI), Di Cristofano, A. (CoPI), Ghossein, R. A. (CoPI) & Seshan, V. E. (CoPI)
9/19/14 → 8/31/20
Project: Research project
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SPORE in Thyroid Cancer
Di Cristofano, A. (PI), Seshan, V. (PI), Chan, T.A. (PI), Ghossein, R. (PI), Berger, M. (PI) & Fagin, J. (PI)
9/19/14 → 8/31/20
Project: Research project
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PI3K-mediated metabolic alterations in the pre-neoplastic thyroid
Di Cristofano, A. (PI), Rose, S. A. (PI) & Rose, S. A. (PI)
1/1/13 → 12/31/17
Project: Research project
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PI3K-mediated metabolic alterations in the pre-neoplastic thyroid
Di Cristofano, A. (CoPI) & Di Cristofano, A. (PI)
1/1/13 → 12/31/17
Project: Research project
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One-Carbon Metabolism Inhibition Depletes Purines and Results in Profound and Prolonged Ewing Sarcoma Growth Suppression
Zirpoli, S., Copperman, N., Patel, S., Forrest, A., Hou, Z., Matherly, L. H., Loeb, D. M. & Di Cristofano, A., Aug 2025, In: Cancer Research Communications. 5, 8, p. 1298-1309 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
SHP2 is a multifunctional target in anaplastic thyroid carcinoma: Cell intrinsic and immune-dependent anti-tumor effects
Marotta, M., Zirpoli, S., Prevete, N., De Simone, C., Di Cristofano, A., Liotti, F. & Melillo, R. M., Sep 2025, In: Biomedicine and Pharmacotherapy. 190, 118384.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
A zebrafish xenotransplant model of anaplastic thyroid cancer to study tumor microenvironment and innate immune cell interactions in vivo
Michael, C., Mendonça-Gomes, J. M., DePaolo, C. W., Di Cristofano, A. & de Oliveira, S., 2024, In: Endocrine-Related Cancer. 31, 7, e230195.Research output: Contribution to journal › Article › peer-review
Open Access -
Anaplastic thyroid cancer cells upregulate mitochondrial one-carbon metabolism to meet purine demand, eliciting a critical targetable vulnerability
Sugarman, A. J., Huynh, L. D., Shabro, A. & Di Cristofano, A., Aug 1 2023, In: Cancer Letters. 568, 216304.Research output: Contribution to journal › Article › peer-review
Open Access9 Link opens in a new tab Scopus citations -
The Year in Basic Thyroid Cancer Research
Di Cristofano, A., Jan 1 2022, In: Thyroid. 32, 1, p. 3-8 6 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations